Invitrogen™ RFXANK Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA565775

Catalog No. PIPA565775

Description

Immunogen sequence: HQLAAQGELDQ LKEHLRKGDN LVNKPDERGF TPLIWASAFG EIETVRFLLE W Highest antigen sequence identity to the following orthologs: Mouse - 90%, Rat - 94%.

Major histocompatibility (MHC) class II molecules are transmembrane proteins that have a central role in development and control of the immune system. The protein encoded by this gene, along with regulatory factor X-associated protein and regulatory factor-5, forms a complex that binds to the X box motif of certain MHC class II gene promoters and activates their transcription. Once bound to the promoter, this complex associates with the non-DNA-binding factor MHC class II transactivator, which controls the cell type specificity and inducibility of MHC class II gene expression. This protein contains ankyrin repeats involved in protein-protein interactions. Mutations in this gene have been linked to bare lymphocyte syndrome type II, complementation group B. Two transcript variants encoding different isoforms have been described for this gene, with only one isoform showing activation activity.

Specifications

• Antigen: RFXANK
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: RFXANK
• Gene Alias: ANKRA1; Ankyrin repeat family A protein 1; ankyrin repeat-containing regulatory factor X-associated protein; BLS; DNA-binding protein RFXANK; F14150_1; regulatory factor X associated ankyrin containing protein; regulatory factor X subunit B; Regulatory factor X-associated ankyrin-containing protein; RFXANK; RFXB; RFX-B; RFX-Bdelta4
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 8625
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Immunocytochemistry
• Concentration: 0.2 mg/mL
• Formulation: PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
• Gene Accession No.: O14593
• Gene Symbols: RFXANK
• Immunogen: Recombinant Human RFXANK. Recombinant protein control fragment (Product #RP-106453).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG