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Invitrogen™ RFXANK Polyclonal Antibody
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Catalog No. PIPA565775
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100 μL
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PIPA565775 100 μL
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Catalog No. PIPA565775 Supplier Invitrogen™ Supplier No. PA565775
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Description

Rabbit Polyclonal Antibody

Immunogen sequence: HQLAAQGELDQ LKEHLRKGDN LVNKPDERGF TPLIWASAFG EIETVRFLLE W Highest antigen sequence identity to the following orthologs: Mouse - 90%, Rat - 94%.

Major histocompatibility (MHC) class II molecules are transmembrane proteins that have a central role in development and control of the immune system. The protein encoded by this gene, along with regulatory factor X-associated protein and regulatory factor-5, forms a complex that binds to the X box motif of certain MHC class II gene promoters and activates their transcription. Once bound to the promoter, this complex associates with the non-DNA-binding factor MHC class II transactivator, which controls the cell type specificity and inducibility of MHC class II gene expression. This protein contains ankyrin repeats involved in protein-protein interactions. Mutations in this gene have been linked to bare lymphocyte syndrome type II, complementation group B. Two transcript variants encoding different isoforms have been described for this gene, with only one isoform showing activation activity.
TRUSTED_SUSTAINABILITY

Specifications

Antigen RFXANK
Applications Immunocytochemistry
Classification Polyclonal
Concentration 0.2 mg/mL
Conjugate Unconjugated
Formulation PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
Gene RFXANK
Gene Accession No. O14593
Gene Alias ANKRA1; Ankyrin repeat family A protein 1; ankyrin repeat-containing regulatory factor X-associated protein; BLS; DNA-binding protein RFXANK; F14150_1; regulatory factor X associated ankyrin containing protein; regulatory factor X subunit B; Regulatory factor X-associated ankyrin-containing protein; RFXANK; RFXB; RFX-B; RFX-Bdelta4
Gene Symbols RFXANK
Host Species Rabbit
Immunogen Recombinant Human RFXANK. Recombinant protein control fragment (Product #RP-106453).
Purification Method Antigen affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 8625
Target Species Human
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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