Invitrogen™ RFXAP Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA568884

Catalog No. PIPA568884

Description

This target displays homology in the following species: Cow: 79%; Dog: 79%; Guinea Pig: 86%; Horse: 79%; Human: 79%; Mouse: 100%; Rabbit: 79%; Rat: 93%.

Major histocompatibility (MHC) class II molecules are transmembrane proteins that have a central role in development and control of the immune system. The protein encoded by this gene, along with regulatory factor X-associated ankyrin-containing protein and regulatory factor-5, forms a complex that binds to the X box motif of certain MHC class II gene promoters and activates their transcription. Once bound to the promoter, this complex associates with the non-DNA-binding factor MHC class II transactivator, which controls the cell type specificity and inducibility of MHC class II gene expression. Mutations in this gene have been linked to bare lymphocyte syndrome type II, complementation group D. Transcript variants utilizing different polyA signals have been found for this gene.

Specifications

• Antigen: RFXAP
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: RFXAP
• Gene Alias: 5730495K23Rik; regulatory factor X associated protein; regulatory factor X-associated protein; RFX DNA-binding complex 36 kDa subunit; RFXAP; RFX-AP; RFX-associated protein; si:ch211-170h2.4
• Host Species: Rabbit
• Purification Method: Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 170767
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Form: Liquid

• Applications: Western Blot
• Concentration: 0.5 mg/mL
• Formulation: PBS with 2% sucrose and 0.09% sodium azide
• Gene Accession No.: Q8VCG9
• Gene Symbols: RFXAP
• Immunogen: synthetic peptide corresponding to a region of mouse RFXAP (aa 51-100).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Mouse
• Product Type: Antibody
• Isotype: IgG