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  5. Tocris Bioscience™ RGFP 966

Tocris Bioscience™ RGFP 966
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Catalog No. 67285
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5 mg
25 mg
Catalog No. Quantity
67-285 5 mg
67-282-5 25 mg
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Catalog No. 67-285

Supplier: Tocris Bioscience™ 6728/5

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Description

Potent and selective HDAC3 inhibitor (IC50 = 80 nM)

RGFP 966 is a potent and selective HDAC3 inhibitor (IC50 = 80 nM); exhibits no effect on other HDAC (up to 15 μM). RGFP 966 reduces the frequency of striatal CAG repeat expansions in mouse models of Huntington's disease and reduces mHTT accumulation. RGFP 966 enhances long-term object-location memory in vivo.

Specifications

Chemical Name or Material (2E)-N-(2-Amino-4-fluorophenyl)-3-[1-(3-phenyl-2-propen-1-yl)-1H-pyrazol-4-yl]-2-propenamide
CAS 1357389-11-7
Quantity 5 mg
Molecular Formula C21H19FN4O
Formula Weight 362.4
Purity 98%
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