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Invitrogen™ RGL1 Polyclonal Antibody
Rabbit Polyclonal Antibody
Supplier: Invitrogen™ PA554081
Description
Immunogen sequence: PHFPCLQKLL DYLTRMMPGS DPERRAQNLL EQFQKQEVET DNGLPNTISF SLEEEEELEG GESAEFTCFS EDLVAEQLTY MDAQLFKKVV PHHCLGCIWS RRD Highest antigen sequence identity to the following orthologs: Mouse - 88%, Rat - 87%.
Ral GDS (Ral guanine nucleotide dissociation stimulator) is a guanine nucleotide exchange factor (GEF) that activates Ral and is implicated in oncogenic Ras-induced cell transformation. RGL1 (ral guanine nucleotide dissociation stimulator-like 1), also known as RGL or RalGDS-like 1, is a 768 amino acid protein that is a putative GEF. Strongly expressed in brain, heart, spleen, kidney and testis, RGL1 is a downstream effector protein that is involved in Ras and Ral signaling pathways. RGL1 contains an N-terminal Ras-GEF domain and a C-terminal Ras-interacting domain that interacts with the GTP-bound form of Ras through its effector loop. Due to its similarity to Ral GDS, RGL1 may be implicated in carcinogenesis. Two isoforms exist due to alternative splicing events.
Specifications
RGL1 | |
Polyclonal | |
Unconjugated | |
RGL1 | |
KIAA0959; mKIAA0959; ral guanine nucleotide dissociation stimulator like 1; ral guanine nucleotide dissociation stimulator,-like 1; ral guanine nucleotide dissociation stimulator-like 1; RalGDS-like 1; RGL; Rgl1 | |
Rabbit | |
Antigen affinity chromatography | |
RUO | |
23179 | |
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. | |
Liquid |
Immunohistochemistry (Paraffin), Immunocytochemistry | |
0.2 mg/mL | |
PBS with 40% glycerol and 0.02% sodium azide; pH 7.2 | |
Q9NZL6 | |
RGL1 | |
Recombinant protein corresponding to Human RGL1. Recombinant protein control fragment (Product #RP-92439). | |
100 μL | |
Primary | |
Human | |
Antibody | |
IgG |
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