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Invitrogen™ RGL1 Polyclonal Antibody
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Catalog No. PIPA5104054
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100 μL
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PIPA5104054 100 μL
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Catalog No. PIPA5104054 Supplier Invitrogen™ Supplier No. PA5104054
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Description

Rabbit Polyclonal Antibody

Antibody detects endogenous levels of total RGL1.

Ral GDS (Ral guanine nucleotide dissociation stimulator) is a guanine nucleotide exchange factor (GEF) that activates Ral and is implicated in oncogenic Ras-induced cell transformation. RGL1 (ral guanine nucleotide dissociation stimulator-like 1), also known as RGL or RalGDS-like 1, is a 768 amino acid protein that is a putative GEF. Strongly expressed in brain, heart, spleen, kidney and testis, RGL1 is a downstream effector protein that is involved in Ras and Ral signaling pathways. RGL1 contains an N-terminal Ras-GEF domain and a C-terminal Ras-interacting domain that interacts with the GTP-bound form of Ras through its effector loop. Due to its similarity to Ral GDS, RGL1 may be implicated in carcinogenesis. Two isoforms exist due to alternative splicing events.
TRUSTED_SUSTAINABILITY

Specifications

Antigen RGL1
Applications Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
Classification Polyclonal
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
Gene RGL1
Gene Accession No. Q60695, Q9NZL6
Gene Alias KIAA0959; mKIAA0959; ral guanine nucleotide dissociation stimulator like 1; ral guanine nucleotide dissociation stimulator,-like 1; ral guanine nucleotide dissociation stimulator-like 1; RalGDS-like 1; RGL; Rgl1
Gene Symbols RGL1
Host Species Rabbit
Immunogen A synthesized peptide derived from human RGL1(Accession Q9NZL6), corresponding to amino acid residues P532-K582.
Purification Method Affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 19731, 23179, 289080
Target Species Human, Mouse, Rat
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov
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