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Invitrogen™ RGL1 Polyclonal Antibody
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Catalog No. PIPA5110289
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100 μL
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PIPA5110289 100 μL
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Catalog No. PIPA5110289 Supplier Invitrogen™ Supplier No. PA5110289
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Description

Rabbit Polyclonal Antibody

Immunogen sequence: LKTQQRAKII EKWINIAHEC RLLKNFSSLR AIVSALQSNS IYRLKKTWAA VPRDRMLMFE ELSDIFSDHN NHLTSRELLM KEGTSKFANL DSSVKENQKR T.

Ral GDS (Ral guanine nucleotide dissociation stimulator) is a guanine nucleotide exchange factor (GEF) that activates Ral and is implicated in oncogenic Ras-induced cell transformation. RGL1 (ral guanine nucleotide dissociation stimulator-like 1), also known as RGL or RalGDS-like 1, is a 768 amino acid protein that is a putative GEF. Strongly expressed in brain, heart, spleen, kidney and testis, RGL1 is a downstream effector protein that is involved in Ras and Ral signaling pathways. RGL1 contains an N-terminal Ras-GEF domain and a C-terminal Ras-interacting domain that interacts with the GTP-bound form of Ras through its effector loop. Due to its similarity to Ral GDS, RGL1 may be implicated in carcinogenesis. Two isoforms exist due to alternative splicing events.
TRUSTED_SUSTAINABILITY

Specifications

Antigen RGL1
Applications ELISA, Western Blot
Classification Polyclonal
Concentration 1.11 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.01% thimerosal; pH 7.3
Gene RGL1
Gene Accession No. Q60695, Q9NZL6
Gene Alias KIAA0959; mKIAA0959; ral guanine nucleotide dissociation stimulator like 1; ral guanine nucleotide dissociation stimulator,-like 1; ral guanine nucleotide dissociation stimulator-like 1; RalGDS-like 1; RGL; Rgl1
Gene Symbols RGL1
Host Species Rabbit
Immunogen A synthetic peptide corresponding to a sequence within amino acids 300-400 of human RGL1 (NP_0012846001).
Purification Method Affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 19731, 23179, 289080
Target Species Human, Mouse, Rat
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Liquid
Isotype IgG
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Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov
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