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Invitrogen™ RGL1 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA537202

Catalog No. PIPA537202


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Description

Description

This antibody detects endogenous protein at a molecular weight of 87 kDa. Purity is >95% by SDS-PAGE.

Ral GDS (Ral guanine nucleotide dissociation stimulator) is a guanine nucleotide exchange factor (GEF) that activates Ral and is implicated in oncogenic Ras-induced cell transformation. RGL1 (ral guanine nucleotide dissociation stimulator-like 1), also known as RGL or RalGDS-like 1, is a 768 amino acid protein that is a putative GEF. Strongly expressed in brain, heart, spleen, kidney and testis, RGL1 is a downstream effector protein that is involved in Ras and Ral signaling pathways. RGL1 contains an N-terminal Ras-GEF domain and a C-terminal Ras-interacting domain that interacts with the GTP-bound form of Ras through its effector loop. Due to its similarity to Ral GDS, RGL1 may be implicated in carcinogenesis. Two isoforms exist due to alternative splicing events.
TRUSTED_SUSTAINABILITY
Specifications

Specifications

RGL1
Polyclonal
Unconjugated
RGL1
KIAA0959; mKIAA0959; ral guanine nucleotide dissociation stimulator like 1; ral guanine nucleotide dissociation stimulator,-like 1; ral guanine nucleotide dissociation stimulator-like 1; RalGDS-like 1; RGL; Rgl1
Rabbit
Antigen Affinity Chromatography
RUO
19731, 23179, 289080
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Liquid
Western Blot
1 mg/mL
PBS with 50% glycerol and 0.02% sodium azide; pH 7.2
Q60695, Q9NZL6
RGL1
A synthetic peptide corresponding to residues in human RGL1.
100 μL
Primary
Human, Mouse, Rat
Antibody
IgG
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