Invitrogen™ RGMB Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA521818

Catalog No. PIPA521818

Description

Recommended positive controls: 293T, A431, H1299, HeLaS3, HepG2, Molt-4, Raji, mouse brain. Predicted reactivity: Mouse (88%), Rhesus Monkey (97%). Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.

Repulsive Guidance Molecule B (RGMB) is primarily expressed in the central nervous system. RGM A and B both appear at every level of the developing neural axis, where they colocalize to a large extent in the mantle layer, although only RGMA appears in the neuroepithelium, and only RGMB in the peripheral nervous system. During development, both RGMA and B appear also in lung and in limb cartilage, while RGMB has additional expression domains in pancreas.

Specifications

• Antigen: RGMB
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: RGMB
• Gene Alias: 1110059F19Rik; DRAGON; DRG11-responsive axonal guidance and outgrowth of neurite; repulsive guidance molecule B; repulsive guidance molecule family member B; RGM domain family member B; RGM domain family, member B; RGMB
• Host Species: Rabbit
• Purification Method: Antigen Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 285704, 68799
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Immunohistochemistry (Paraffin), Western Blot
• Concentration: 1 mg/mL
• Formulation: 0.1M tris glycine with 10% glycerol and 0.01% thimerosal; pH 7
• Gene Accession No.: Q6NW40, Q7TQ33
• Gene Symbols: RGMB
• Immunogen: Recombinant fragment corresponding to a region within amino acids 178 and 437 of RGMB (Uniprot ID#Q6NW40).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse
• Product Type: Antibody
• Isotype: IgG