Invitrogen™ RGR Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA534154

Catalog No. PIPA534154

Description

Percent identity with other species by BLAST analysis: Human, Gibbon, Monkey, Marmoset (100%) Bovine, Horse, Pig (94%) Dog, Bat, Elephant (88%) Mouse, Rat, Hamster (81%).

This gene encodes a putative retinal G-protein coupled receptor. The gene is a member of the opsin subfamily of the 7 transmembrane, G-protein coupled receptor 1 family. Like other opsins which bind retinaldehyde, it contains a conserved lysine residue in the seventh transmembrane domain. The protein acts as a photoisomerase to catalyze the conversion of all-trans-retinal to 11-cis-retinal. The reverse isomerization occurs with rhodopsin in retinal photoreceptor cells. The protein is exclusively expressed in tissue adjacent to retinal photoreceptor cells, the retinal pigment epithelium and Mueller cells. This gene may be associated with autosomal recessive and autosomal dominant retinitis pigmentosa (arRP and adRP, respectively). Alternative splicing results in multiple transcript variants encoding different isoforms.

Specifications

• Antigen: RGR
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: RGR
• Gene Alias: retinal G protein coupled receptor; Rgr; RGR opsin; RGR-opsin; RP44; RPE retinal G-protein coupled receptor; RPE-retinal G protein-coupled receptor
• Host Species: Rabbit
• Purification Method: Antigen Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 5995
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Immunohistochemistry (Paraffin)
• Concentration: 1 mg/mL
• Formulation: PBS with 0.1% sodium azide
• Gene Accession No.: P47804
• Gene Symbols: RGR
• Immunogen: Synthetic 16 amino acid peptide from 1st extracellular domain of human RGR.
• Quantity: 50 μg
• Primary or Secondary: Primary
• Target Species: Human, Monkey
• Product Type: Antibody
• Isotype: IgG

Safety and Handling

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