RGS13 Mouse anti-Human, Clone: OTI5D7, lyophilized, TrueMAB™

Catalog No.	Quantity
50-166-9713	100 μg

Catalog No. 50-166-9713 Supplier OriGene Supplier No. CF809778

Description

Mouse Monoclonal Antibody

Reconstitute with PBS (pH 7.3) and recommend to perform another round of desalting process using Product No. 7KMWCO

RGS13 is the smallest member of the mammalian gene family, RGS (regulators of G protein-signaling) which are structural and functional homologues of yeast SST2 and C. elegans egl-10 proteins. RGS proteins attenuate G protein-mediated pathways by acting as GTPase-activating proteins (GAPs) for Ga subunits. RGS13 has been found most abundantly in human tonsil, thymus, lung, lymph node, and spleen. RGS13 regulate Gai, Gaq, and Gas coupled signaling cascades. It is a GTPase-activating protein for Gai and Gao. The protein blocks MAPK activity induced by Gai- or Gaq-coupled receptors. The protein also attenuates GTPase-deficient Gaq (GaqQL) mediated cAMP response element activation. The gene encoding for human RGS13 is localized on chromosome 1q31.2.

Specifications

• Antigen: RGS13
• Applications: Immunohistochemistry (Paraffin), Western Blot
• Classification: Monoclonal
• Clone: OTI5D7
• Conjugate: Unconjugated
• Formulation: PBS with 8% trehalose and no preservative; pH 7.3
• Gene: RGS13
• Gene Accession No.: O14921
• Gene Alias: regulator of G protein signaling 13
• Gene Symbols: RGS13
• Host Species: Mouse
• Immunogen: Full length human recombit protein of human RGS13 produced in E.coli.
• Purification Method: Affinity Chromatography
• Quantity: 100 μg
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Gene ID (Entrez): 6003
• Target Species: Human
• Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
• Product Type: Antibody
• Form: Lyophilized
• Isotype: IgG1