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Invitrogen™ RGS13 Polyclonal Antibody
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Catalog No. PIPA5110290
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100 μL
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PIPA5110290 100 μL
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Catalog No. PIPA5110290 Supplier Invitrogen™ Supplier No. PA5110290
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Description

Rabbit Polyclonal Antibody

Immunogen sequence: MSRRNCWICK MCRDESKRPP SNLTLEEVLQ WAQSFENLMA TKYGPVVYAA YLKMEHSDEN IQFWMACETY KKIASRWSRI SRAKKLYKIY IQPQSPREIN IDSSTRETII RNIQEPTETC FEEAQKIVYM HMERDSYPRF LKSEMYQKLL KTMQSNNSF.

RGS13 is the smallest member of the mammalian gene family, RGS (regulators of G protein-signaling) which are structural and functional homologues of yeast SST2 and C. elegans egl-10 proteins. RGS proteins attenuate G protein-mediated pathways by acting as GTPase-activating proteins (GAPs) for Ga subunits. RGS13 has been found most abundantly in human tonsil, thymus, lung, lymph node, and spleen. RGS13 regulate Gai, Gaq, and Gas coupled signaling cascades. It is a GTPase-activating protein for Gai and Gao. The protein blocks MAPK activity induced by Gai- or Gaq-coupled receptors. The protein also attenuates GTPase-deficient Gaq (GaqQL) mediated cAMP response element activation. The gene encoding for human RGS13 is localized on chromosome 1q31.2.
TRUSTED_SUSTAINABILITY

Specifications

Antigen RGS13
Applications ELISA, Western Blot
Classification Polyclonal
Concentration 0.65 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
Gene RGS13
Gene Accession No. Q8K443
Gene Alias MGC17173; regulator of G protein signaling 13; regulator of G-protein signaling 13; regulator of G-protein signalling 13; RGD1562103; Rgs13; RP11-92K2.1
Gene Symbols RGS13
Host Species Rabbit
Immunogen Recombinant fusion protein containing a sequence corresponding to amino acids 1-159 of human RGS13 (NP_002918.1).
Purification Method Affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 246709, 498246
Target Species Mouse, Rat
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Liquid
Isotype IgG
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Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov
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