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Invitrogen™ RGS13 Polyclonal Antibody
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Catalog No. PIPA568626
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100 μL
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PIPA568626 100 μL
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Catalog No. PIPA568626 Supplier Invitrogen™ Supplier No. PA568626
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Description

Rabbit Polyclonal Antibody

This target displays homology in the following species: Cow: 100%; Dog: 100%; Horse: 92%; Human: 100%; Mouse: 93%; Rabbit: 93%; Rat: 100%.

RGS13 is the smallest member of the mammalian gene family, RGS (regulators of G protein-signaling) which are structural and functional homologues of yeast SST2 and C. elegans egl-10 proteins. RGS proteins attenuate G protein-mediated pathways by acting as GTPase-activating proteins (GAPs) for Ga subunits. RGS13 has been found most abundantly in human tonsil, thymus, lung, lymph node, and spleen. RGS13 regulate Gai, Gaq, and Gas coupled signaling cascades. It is a GTPase-activating protein for Gai and Gao. The protein blocks MAPK activity induced by Gai- or Gaq-coupled receptors. The protein also attenuates GTPase-deficient Gaq (GaqQL) mediated cAMP response element activation. The gene encoding for human RGS13 is localized on chromosome 1q31.2.
TRUSTED_SUSTAINABILITY

Specifications

Antigen RGS13
Applications Immunohistochemistry, Western Blot
Classification Polyclonal
Concentration 1.0 mg/mL
Conjugate Unconjugated
Formulation PBS with 2% sucrose and 0.09% sodium azide
Gene RGS13
Gene Accession No. O14921
Gene Alias MGC17173; regulator of G protein signaling 13; regulator of G-protein signaling 13; regulator of G-protein signalling 13; RGD1562103; Rgs13; RP11-92K2.1
Gene Symbols RGS13
Host Species Rabbit
Immunogen synthetic peptide directed towards the middle region of human RGS13.
Purification Method Protein A
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 6003
Target Species Human
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Liquid
Isotype IgG
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Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov
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