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RGS14 Rabbit anti-Human, Mouse, Polyclonal, Proteintech
SDP

Rabbit Polyclonal Antibody

Manufacturer:  Proteintech Group Inc 162581AP150UL

Encompass_Preferred

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Catalog No. 50-173-0834


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Description

Description

This gene encodes a member of the regulator of G-protein signaling family. This protein contains one RGS domain, two Raf-like Ras-binding domains (RBDs), and one GoLoco domain. The protein attenuates the signaling activity of G-proteins by binding, through its GoLoco domain, to specific types of activated, GTP-bound G alpha subunits. Acting as a GTPase activating protein (GAP), the protein increases the rate of conversion of the GTP to GDP. This hydrolysis allows the G alpha subunits to bind G beta/gamma subunit heterodimers, forming inactive G-protein heterotrimers, thereby terminating the signal. Alternate transcriptional splice variants of this gene have been observed but have not been thoroughly characterized.
Specifications

Specifications

RGS14
Polyclonal
Unconjugated
RGS14
RGS14
Rabbit
Antigen Affinity Chromatography
RUO
10636, 51791
-20°C
Liquid
Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot
0.33 mg/mL
PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
O43566, P97492
Rgs14
RGS14 Fusion Protein Ag9292
150 μL
Primary
Human, Mouse
Antibody
IgG
SDS
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