Invitrogen™ RGS18 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA523112

Catalog No. PIPA523112

Description

RGS18 Polyclonal Antibody for Western Blot, ICC/IF

This gene encodes a member of the regulator of G-protein signaling family. This protein is contains a conserved, 120 amino acid motif called the RGS domain. The protein attenuates the signaling activity of G-proteins by binding to activated, GTP-bound G alpha subunits and acting as a GTPase activating protein (GAP), increasing the rate of conversion of the GTP to GDP. This hydrolysis allows the G alpha subunits to bind G beta/gamma subunit heterodimers, forming inactive G-protein heterotrimers, thereby terminating the signal. Alternate transcriptional splice variants of this gene have been observed but have not been thoroughly characterized.

Specifications

• Antigen: RGS18
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: RGS18
• Gene Alias: regulator of G-protein signaling 18; regulator of G-protein signalling 13; regulator of G-protein signalling 18; RGS13; RGS18; RP11-142L4.1
• Host Species: Rabbit
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse
• Product Type: Antibody
• Isotype: IgG

• Applications: Western Blot, Immunocytochemistry
• Concentration: Conc. Not Determined
• Formulation: Whole serum with 50% glycerol and 0.025% sodium azide
• Gene Accession No.: Q99PG4, Q9NS28
• Gene Symbols: RGS18
• Immunogen: Within the range of amino acids 30-62 of human RGS18 protein.
• Regulatory Status: RUO
• Gene ID (Entrez): 64214, 64407
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Form: Liquid

Safety and Handling

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