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Invitrogen™ RGS21 Polyclonal Antibody
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Catalog No. PIPA520760
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100 μg
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Catalog No. Quantity
PIPA520760 100 μg
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Catalog No. PIPA520760 Supplier Invitrogen™ Supplier No. PA520760
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Description

Rabbit Polyclonal Antibody

A suggested positive control is HepG2 cell lysate. PA5-20760 can be used with blocking peptide PEP-0874.

Regulator of G-protein signaling (RGS) proteins contain an 120 amino acid conserved domain, termed the RGS domain, that acts as a GTPase-activating protein that acts to reduce the signal transmitted by the receptor-activated G-alpha subunit. RGS21 is a recently identified member of this family that has been reported to be selectively expressed in subpopulations of taste bud cells and co-expressed with bitter and sweet transduction components such as alpha-gusticin, phospholipase Cbeta2, T1R2/T1R3 sweet taste receptors and T2R bitter taste receptors. Other reports indicate that RGS21 is more widely expressed. Binding assays demonstrate that RGS21 binds alpha-gusticin in a conformation-dependent manner and may do the same with T1R receptors, suggesting that RGS21 may play a role in sweet and bitter taste transduction processes.
TRUSTED_SUSTAINABILITY

Specifications

Antigen RGS21
Applications Immunohistochemistry, Western Blot, Immunocytochemistry
Classification Polyclonal
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 0.02% sodium azide
Gene RGS21
Gene Accession No. Q2M5E4
Gene Alias EG624910; regulator of G-protein signaling 21; regulator of G-protein signalling 21; RGS21
Gene Symbols RGS21
Host Species Rabbit
Immunogen A 16 amino acid peptide near the center of human RGS21.
Purification Method Antigen affinity chromatography
Quantity 100 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 431704
Target Species Human
Content And Storage Maintain refrigerated at 2°C to 8°C for up to 3 months. For long term storage store at -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov
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