Invitrogen™ RGS4 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA595929

Catalog No. PIPA595929

Description

Immunogen sequence: MCKGLAGLPA SCLRSAKDMK HRLGFLLQKS DSCEHNSSHN KKDKVVICQR VSQEEVKKWA ESLENLISHE CGLAAFKAFL KSEYSEENID FWISCEEYKK Positive Samples: U-251MG, HeLa, A-375, Jurkat, Raji.

Regulator of G protein signaling (RGS) family members are regulatory molecules that act as GTPase activating proteins (GAPs) for G alpha subunits of heterotrimeric G proteins. RGS proteins are able to deactivate G protein subunits of the Gi alpha, Go alpha and Gq alpha subtypes. They drive G proteins into their inactive GDP-bound forms. Regulator of G protein signaling 4 belongs to this family. All RGS proteins share a conserved 120-amino acid sequence termed the RGS domain. Regulator of G protein signaling 4 protein is 37% identical to RGS1 and 97% identical to rat Rgs4. This protein negatively regulate signaling upstream or at the level of the heterotrimeric G protein and is localized in the cytoplasm. Alternatively spliced transcript variants have been found for this gene.

Specifications

• Antigen: RGS4
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: RGS4
• Gene Alias: AA004315; AA597169; ESTM48; ESTM50; MGC2124; MGC60244; regulator of G protein signaling 4; regulator of G protein signaling 4; regulator of G-protein signaling 4; regulator of G-protein signaling 4; regulator of G-protein signalling 4; RGP4; RGS4; RP11-430G6.1; schizophrenia disorder 9; SCZD9; similar to Regulator of G-protein signaling 4 (RGS4) (RGP4)
• Host Species: Rabbit
• Purification Method: Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 19736, 29480, 5999
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Form: Liquid

• Applications: ELISA, Western Blot, Immunocytochemistry
• Concentration: 0.47 mg/mL
• Formulation: PBS with 50% glycerol and 0.01% thimerosal; pH 7.3
• Gene Accession No.: O08899, P49798, P49799
• Gene Symbols: RGS4
• Immunogen: A synthetic peptide corresponding to a sequence within amino acids 1-100 of human RGS4 (NP_0056041).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rat
• Product Type: Antibody
• Isotype: IgG

Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov