Promotional price valid on web orders only. Your contract pricing may differ. Interested in signing up for a dedicated account number?
Learn More
  1. Home
  2. Products
  3. Antibodies
  4. Primary Antibodies
  5. All Primary Antibodies
  6. PIPA520862

Invitrogen™ RHBDD3 Polyclonal Antibody
GREENER_CHOICE

Catalog No. PIPA520862
Change view
Click to view available options
Quantity:
100 μg
1 product options available for selection
Product selection table with 1 available options. Use arrow keys to navigate and Enter or Space to select.
Catalog No. Quantity
PIPA520862 100 μg
Use arrow keys to navigate between rows. Press Enter or Space to select a product option. 1 options available.
1 options
Catalog No. PIPA520862 Supplier Invitrogen™ Supplier No. PA520862
Add to Cart
Add to Cart

Description

Rabbit Polyclonal Antibody

A suggested positive control is rat lung tissue lysate. PA5-20862 can be used with blocking peptide PEP-0976.

The Rhomboid family of proteins is made up of several widely conserved polytopic membrane serine proteases that play roles in growth and development. RHBDD3 was initially identified as a novel pituitary tumor apoptosis gene (PTAG) whose expression was reduced in certain pituitary adenomas. Overexpression of RHBDD3 in AtT20 cells showed an increase in apoptotic activity and caspase activation in response to bromocriptine, and apoptosis-inducing dopamine D2 analog, suggesting that reactivation of RHBDD3 in tumors may be a therapeutically useful tool. Later experiments also showed that RHBDD3 expression is also reduced in several primary colorectal tumors, indicating that loss of RHBDD3 contributes to a blunted apoptotic response and probably predisposes cells towards malignant transformation.
TRUSTED_SUSTAINABILITY

Specifications

Antigen RHBDD3
Applications Immunohistochemistry, Western Blot
Classification Polyclonal
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 0.02% sodium azide
Gene RHBDD3
Gene Accession No. Q642B3, Q8BP97, Q9Y3P4
Gene Alias C22orf3; CTA-984G1.4; HS984G1A; pituitary tumor apoptosis; pituitary-derived proapoptotic; PTAG; RGD1311827; Rhbdd3; rhomboid domain containing 3; rhomboid domain-containing protein 3
Gene Symbols RHBDD3
Host Species Rabbit
Immunogen A 13 amino acid peptide from near the center of human RHBDD3.
Purification Method Antigen Affinity Chromatography
Quantity 100 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 25807, 279766, 289753
Target Species Human, Mouse, Rat
Content And Storage Maintain refrigerated at 2-8°C for up to 3 months. For long term storage store at -20°C
Product Type Antibody
Form Liquid
Isotype IgG
Show More Show Less

Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov
Product Title
Select an issue

By clicking Submit, you acknowledge that you may be contacted by Fisher Scientific in regards to the feedback you have provided in this form. We will not share your information for any other purposes. All contact information provided shall also be maintained in accordance with our Privacy Policy.