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Invitrogen™ RHEB Polyclonal Antibody
Rabbit Polyclonal Antibody
Supplier: Invitrogen™ PA5110294
Description
Immunogen sequence: MPQSKSRKIA ILGYRSVGKS SLTIQFVEGQ FVDSYDPTIE NTFTKLITVN GQEYHLQLVD TAGQDEYSIF PQTYSIDING YILVYSVTSI KSFEVIKVIH GKLLDMVGKV QIPIMLVGNK KDLHMERVIS YEEGKALAES WNAAFLESSA KENQTAVDVF RRIILEAEKM DGAASQGKSS.
Rheb encodes a member of the small GTPase superfamily and encodes a lipid-anchored, cell membrane protein with five repeats of the RAS-related GTP-binding region. This protein is vital in regulation of growth and cell cycle progression due to its role in the insulin/TOR/S6K signaling pathway. The protein has GTPase activity and shuttles between a GDP-bound form and a GTP-bound form, and farnesylation of the protein is required for this activity. Three pseudogenes have been mapped, two on chromosome 10 and one on chromosome 22.
Specifications
RHEB | |
Polyclonal | |
Unconjugated | |
RHEB | |
GTP-binding protein Rheb; Ras homolog enriched in brain; Ras homolog enriched in brain 2; RAS-homolog enriched in brain; RHEB; Rheb1; RHEB2 | |
Rabbit | |
Affinity Chromatography | |
RUO | |
19744, 6009 | |
-20°C, Avoid Freeze/Thaw Cycles | |
Liquid |
ELISA, Western Blot, Immunocytochemistry | |
1.45 mg/mL | |
PBS with 50% glycerol and 0.05% ProClin 300; pH 7.3 | |
Q15382, Q921J2 | |
RHEB | |
Recombinant fusion protein containing a sequence corresponding to amino acids 1-180 of human RheB (NP_0056051). | |
100 μL | |
Primary | |
Human, Mouse | |
Antibody | |
IgG |
Safety and Handling
WARNING: Cancer - www.P65Warnings.ca.gov
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