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Invitrogen™ RHEB Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA5110294

Catalog No. PIPA5110294


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Description

Description

Immunogen sequence: MPQSKSRKIA ILGYRSVGKS SLTIQFVEGQ FVDSYDPTIE NTFTKLITVN GQEYHLQLVD TAGQDEYSIF PQTYSIDING YILVYSVTSI KSFEVIKVIH GKLLDMVGKV QIPIMLVGNK KDLHMERVIS YEEGKALAES WNAAFLESSA KENQTAVDVF RRIILEAEKM DGAASQGKSS.

Rheb encodes a member of the small GTPase superfamily and encodes a lipid-anchored, cell membrane protein with five repeats of the RAS-related GTP-binding region. This protein is vital in regulation of growth and cell cycle progression due to its role in the insulin/TOR/S6K signaling pathway. The protein has GTPase activity and shuttles between a GDP-bound form and a GTP-bound form, and farnesylation of the protein is required for this activity. Three pseudogenes have been mapped, two on chromosome 10 and one on chromosome 22.
TRUSTED_SUSTAINABILITY
Specifications

Specifications

RHEB
Polyclonal
Unconjugated
RHEB
GTP-binding protein Rheb; Ras homolog enriched in brain; Ras homolog enriched in brain 2; RAS-homolog enriched in brain; RHEB; Rheb1; RHEB2
Rabbit
Affinity Chromatography
RUO
19744, 6009
-20°C, Avoid Freeze/Thaw Cycles
Liquid
ELISA, Western Blot, Immunocytochemistry
1.45 mg/mL
PBS with 50% glycerol and 0.05% ProClin 300; pH 7.3
Q15382, Q921J2
RHEB
Recombinant fusion protein containing a sequence corresponding to amino acids 1-180 of human RheB (NP_0056051).
100 μL
Primary
Human, Mouse
Antibody
IgG
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