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Invitrogen™ Rhizopus arrhizus Monoclonal Antibody (WSSA-RA-1)
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Catalog No. PIMA174435
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250 μg
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PIMA174435 250 μg
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Catalog No. PIMA174435 Supplier Invitrogen™ Supplier No. MA174435
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Description

Mouse Monoclonal Antibody

This clone recognizes Rhizopus arrhizus and other members of the family Mucoraceae including Absidia corymbifera and Rhizomucor pusillus, reacting strongly with the cytoplasm of hyphae and also possibly with the walls and septae, where present. It has been successfully used in immunohistochemistry for the specific and consistent in situ diagnosis of systemic bovine zygomycosis, attributed to its possible binding to a highly glycosylated moiety on non-structural components. This clone does not bind to water-soluble somatic antigens (WSSA) of Aspergillus spp. In Western blot, this antibody detects a number diffuse band/s of between ~14-110kDa of Rhizopus arrhizus water-soluble somatic antigens. IHC staining requires protein digestion pre-treatment of paraffin sections using trypsin or pronase. Recommended postive control: lymph nodes from R. arrhizus infected cattle.

R. arrhizus is an angio-invasive filamentous fungus. It is one of the main causative agents of systemic bovine and human zygomycosis, a worldwide and often fatal respiratory disease.
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Specifications

Antigen Rhizopus arrhizus
Applications ELISA, Immunohistochemistry (Paraffin), Western Blot
Classification Monoclonal
Clone WSSA-RA-1
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 0.09% sodium azide
Gene Alias R. Arrhizus
Host Species Mouse
Immunogen Water-soluble somatic antigens from Rhizopus arrhizus.
Purification Method Ammonium Sulfate Precipitation
Quantity 250 μg
Regulatory Status RUO
Primary or Secondary Primary
Target Species Fungi
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgM
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