RHOB Rabbit anti-Human, Mouse, Polyclonal, Proteintech

Catalog No.	Quantity
50-172-9367	150 μL

Catalog No. 50-172-9367 Supplier Proteintech Group Inc Supplier No. 143261AP150UL

Description

Rabbit Polyclonal Antibody

RhoB (Rho-related GTP-binding protein) mediates apoptosis in neoplastically transformed cells after DNA damage. While not essential for development, it does affect cell adhesion and growth factor signaling in transformed cells. RhoB targets PKN1 to endosomes and is involved in trafficking of the EGF receptor from late endosomes to lysosomes. Also required for stability and nuclear trafficking of AKT1/AKT which promotes endothelial cell survival during vascular development. Serves as a tumor supressor - deletion of RhoB causes tumor formation.

Specifications

• Antigen: RHOB
• Applications: Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot
• Classification: Polyclonal
• Concentration: 0.2 mg/mL
• Conjugate: Unconjugated
• Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
• Gene: RHOB
• Gene Accession No.: P62745, P62746
• Gene Alias: ARH6, ARHB, h6, MST081, MSTP081, Rho cDNA clone 6, RHOB, RHOH6
• Gene Symbols: RHOB
• Host Species: Rabbit
• Immunogen: RHOB Fusion Protein Ag5593
• Purification Method: Antigen Affinity Chromatography
• Quantity: 150 μL
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Gene ID (Entrez): 11852, 388
• Target Species: Human, Mouse
• Content And Storage: -20°C
• Product Type: Antibody
• Form: Liquid
• Isotype: IgG