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Invitrogen™ RhoB Recombinant Superclonal™ Antibody (19HCLC)

Rabbit Recombinant Superclonal Antibody

Supplier:  Invitrogen™ 711274

Catalog No. 71-127-4


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Description

Description

This antibody is predicted to react with Mouse, Monkey, Goat and Cat. Recombinant rabbit Superclonal™ antibodies are unique offerings from Thermo Fisher Scientific. They are comprised of a selection of multiple different recombinant monoclonal antibodies, providing the best of both worlds - the sensitivity of polyclonal antibodies with the specificity of monoclonal antibodies - all delivered with the consistency only found in a recombinant antibody. While functionally the same as a polyclonal antibody - recognizing multiple epitope sites on the target and producing higher detection sensitivity for low abundance targets - a recombinant rabbit Superclonal™ antibody has a known mixture of light and heavy chains. The exact population can be produced in every lot, circumventing the biological variability typically associated with polyclonal antibody production. Note: Formerly called Recombinant polyclonal antibody, this product is now rebranded as Recombinant Superclonal™ antibody. The physical product and the performance remain unchanged.

Rho-related GTP-binding protein (RhoB) mediates apoptosis in neoplastically transformed cells after DNA damage. While not essential for development, it does affect cell adhesion and growth factor signaling in transformed cells. RhoB targets PKN1 to endosomes and is involved in trafficking of the EGF receptor from late endosomes to lysosomes. Also required for stability and nuclear trafficking of AKT1/AKT which promotes endothelial cell survival during vascular development. Serves as a tumor supressor - deletion of RhoB causes tumor formation.
TRUSTED_SUSTAINABILITY
Specifications

Specifications

RhoB
Recombinant Superclonal
0.5 mg/mL
PBS with 0.09% sodium azide; pH 7.2
P62745, P62746, P62747
RHOB
Peptides corresponding to Human RHOB (aa 128-145, 50-65).
100 μg
Primary
Human, Mouse, Rat
Antibody
IgG
Western Blot, Immunocytochemistry
19HCLC
Unconjugated
RHOB
AA017882; Aplysia RAS-related homolog 6; aplysia ras-related homolog B; Arh6; Arhb; h6; MST081; MSTP081; oncogene RHO H6; ras homolog B; ras homolog family member B; ras homolog gene family, member AB; ras homolog gene family, member B; Rho; rho cDNA clone 6; rhoB; RHOH6; Rho-related GTP-binding protein RhoB
Rabbit
Protein A
RUO
11852, 388, 64373
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Liquid
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