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Invitrogen™ RhoBTB1 Polyclonal Antibody
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Catalog No. PIPA542077
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100 μL
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PIPA542077 100 μL
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Catalog No. PIPA542077 Supplier Invitrogen™ Supplier No. PA542077
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Description

Rabbit Polyclonal Antibody

Peptide sequence: DNQEYFERHR WPPVWYLKEE DHYQRVKRER EKEDIALNKH RSRRKWCFWN Sequence homology: Cow: 100%; Dog: 100%; Goat: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100%; Sheep: 79%; Zebrafish: 93%.

RHOBTB1 (Rho-related BTB domain-containing protein 1) and RHOBTB3 (Rho-related BTB domain-containing protein 3) each contain two BTB (POZ) domains and belong to the RhoBTB subfamily of Rho GTPases. Members of the RhoBTB subfamily are evolutionarily conserved and are characterized by a proline-rich region, a GTPase domain and two tandem BTB repeats. While both RHOBTB1 and RHOBTB3 are expressed ubiquitously, RHOBTB1 is found at high levels in placenta, stomach, testis, kidney and skeletal muscle, whereas RHOBTB3 is found at high levels in neural and cardiac tissues. RHOBTB1 is thought to play a role in GTPase-mediated signaling and may participate in organization of the Actin filament system. Additionally, RHOBTB1 expression is decreased in head and neck carcinomas, suggesting a possible role for RHOBTB1 as a tumor suppressor.
TRUSTED_SUSTAINABILITY

Specifications

Antigen RhoBTB1
Applications Immunohistochemistry (Paraffin), Western Blot
Classification Polyclonal
Concentration 0.5 mg/mL
Conjugate Unconjugated
Formulation PBS with 2% sucrose and 0.09% sodium azide
Gene RHOBTB1
Gene Accession No. O94844
Gene Alias 1700008H16Rik; 3110048G13Rik; AI173445; AI573858; AV350930; DBC2; KIAA0717; KIAA0740; MGC33059; MGC33841; p83; Rho related BTB domain containing 1; Rhobtb1; RHOBTB2; Rho-related BTB domain containing 1; rho-related BTB domain-containing protein 1; zmp:0000000868
Gene Symbols RHOBTB1
Host Species Rabbit
Immunogen Synthetic peptide directed towards the middle region of human RHOBTB1.
Purification Method Affinity Chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 9886
Target Species Human
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Liquid
Isotype IgG
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