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Invitrogen™ RhoBTB1 Polyclonal Antibody
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Catalog No. PIPA531890
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100 μL
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PIPA531890 100 μL
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Catalog No. PIPA531890 Supplier Invitrogen™ Supplier No. PA531890
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Rabbit Polyclonal Antibody

Recommended positive controls: A431, Raji. Predicted reactivity: Mouse (90%), Rat (90%), Chicken (83%), Rhesus Monkey (98%), Chimpanzee (98%), Bovine (95%). Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.

RHOBTB1 (Rho-related BTB domain-containing protein 1) and RHOBTB3 (Rho-related BTB domain-containing protein 3) each contain two BTB (POZ) domains and belong to the RhoBTB subfamily of Rho GTPases. Members of the RhoBTB subfamily are evolutionarily conserved and are characterized by a proline-rich region, a GTPase domain and two tandem BTB repeats. While both RHOBTB1 and RHOBTB3 are expressed ubiquitously, RHOBTB1 is found at high levels in placenta, stomach, testis, kidney and skeletal muscle, whereas RHOBTB3 is found at high levels in neural and cardiac tissues. RHOBTB1 is thought to play a role in GTPase-mediated signaling and may participate in organization of the Actin filament system. Additionally, RHOBTB1 expression is decreased in head and neck carcinomas, suggesting a possible role for RHOBTB1 as a tumor suppressor.
TRUSTED_SUSTAINABILITY

Specifications

Antigen RhoBTB1
Applications Western Blot
Classification Polyclonal
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 1% BSA, 20% glycerol and 0.01% thimerosal; pH 7
Gene RHOBTB1
Gene Accession No. O94844
Gene Alias 1700008H16Rik; 3110048G13Rik; AI173445; AI573858; AV350930; DBC2; KIAA0717; KIAA0740; MGC33059; MGC33841; p83; Rho related BTB domain containing 1; Rhobtb1; RHOBTB2; Rho-related BTB domain containing 1; rho-related BTB domain-containing protein 1; zmp:0000000868
Gene Symbols RHOBTB1
Host Species Rabbit
Immunogen Recombinant protein encompassing a sequence within the center region of human RHOBTB1. The exact sequence is proprietary.
Purification Method Antigen affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 9886
Target Species Human
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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