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Invitrogen™ RhoG Polyclonal Antibody
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Catalog No. PIPA536608
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PIPA536608 100 μL
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Catalog No. PIPA536608 Supplier Invitrogen™ Supplier No. PA536608
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Description

Rabbit Polyclonal Antibody

This antibody detects endogenous protein at a molecular weight of 21 kDa. Purity is >95% by SDS-PAGE.

The Ras p21 family of guanine nucleotide proteins has been widely studied in view of its apparent role in signal transduction pathways and high frequency of mutations in human malignancies. It is now clear, however, that the Ras proteins (H-, K- and N-Ras p21) are members of a much larger superfamily of related proteins. Six members of this family, Rap 1A, Rap 1B, Rap 2, R-Ras, Ral A and Ral B, exhibit approximately 50% amino acid homology to Ras. The six mammalian Rho proteins (Rho A, B, C, G, 7 and 8) are approximately 30% homologous to Ras and are expressed in a wide range of cell types. Both Ras p21 and Rho p21, as well as other members of the Ras superfamily, contain a carboxy-terminal CAAX sequence (C, cysteine; A, aliphatic amino acid; X, any amino acid) which in the case of Ras has been shown to be essential for correct localization and function.
TRUSTED_SUSTAINABILITY

Specifications

Antigen RhoG
Applications Immunohistochemistry (Paraffin), Western Blot
Classification Polyclonal
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.02% sodium azide; pH 7.2
Gene RHOG
Gene Accession No. P84095, P84096
Gene Alias 2810426G09Rik; aplysia ras-related homolog G (RhoG); Arhg; ras homolog family member G; ras homolog G (RhoG); ras homolog gene family, member G; ras homolog gene family, member G (rho G); Rho G; Rhog; rho-related GTP-binding protein RhoG; Sid 10750; Sid10750
Gene Symbols RHOG
Host Species Rabbit
Immunogen Synthetic peptide corresponding to amino acids 100-150 of human Rho G.
Purification Method Antigen affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 308875, 391, 56212
Target Species Human, Mouse, Rat
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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