Invitrogen™ RhoG Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA536608

Catalog No. PIPA536608

Description

This antibody detects endogenous protein at a molecular weight of 21 kDa. Purity is >95% by SDS-PAGE.

The Ras p21 family of guanine nucleotide proteins has been widely studied in view of its apparent role in signal transduction pathways and high frequency of mutations in human malignancies. It is now clear, however, that the Ras proteins (H-, K- and N-Ras p21) are members of a much larger superfamily of related proteins. Six members of this family, Rap 1A, Rap 1B, Rap 2, R-Ras, Ral A and Ral B, exhibit approximately 50% amino acid homology to Ras. The six mammalian Rho proteins (Rho A, B, C, G, 7 and 8) are approximately 30% homologous to Ras and are expressed in a wide range of cell types. Both Ras p21 and Rho p21, as well as other members of the Ras superfamily, contain a carboxy-terminal CAAX sequence (C, cysteine; A, aliphatic amino acid; X, any amino acid) which in the case of Ras has been shown to be essential for correct localization and function.

Specifications

• Antigen: RhoG
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: RHOG
• Gene Alias: 2810426G09Rik; aplysia ras-related homolog G (RhoG); Arhg; ras homolog family member G; ras homolog G (RhoG); ras homolog gene family, member G; ras homolog gene family, member G (rho G); Rho G; Rhog; rho-related GTP-binding protein RhoG; Sid 10750; Sid10750
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 308875, 391, 56212
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Immunohistochemistry (Paraffin), Western Blot
• Concentration: 1 mg/mL
• Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.2
• Gene Accession No.: P84095, P84096
• Gene Symbols: RHOG
• Immunogen: Synthetic peptide corresponding to amino acids 100-150 of human Rho G.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rat
• Product Type: Antibody
• Isotype: IgG