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Invitrogen™ RhoGAP Polyclonal Antibody
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Catalog No. PIPA577867
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100 μL
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Catalog No. Quantity
PIPA577867 100 μL
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Catalog No. PIPA577867 Supplier Invitrogen™ Supplier No. PA577867
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Description

Rabbit Polyclonal Antibody

Positive Control: ARHGAP1 transfected 293T cell Predicted Reactivity: Mouse (99%), Rat (99%), Dog (99%), Rhesus Monkey (99%), Bovine (98%) Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.

The p190 RhoGAP protein is associated with p120 RasGAP in growth-factor stimulated and tyrosine kinase transformed cells. It functions as a GTPase - activating protein (GAP) for Rho and Rac family proteins, which are involved in regulating cytoskeletal actin and membrane ruffling. The antibody appears to couple signal transduction via Ras and Rho through its association with RasGAP. The presence of two adjacent SH2 domains in the p21 RAS GAP indicates that GAP might interact directly with tyrosine kinases.
TRUSTED_SUSTAINABILITY

Specifications

Antigen RhoGAP
Applications Western Blot, Immunocytochemistry
Classification Polyclonal
Concentration 0.31 mg/mL
Conjugate Unconjugated
Formulation PBS with 20% glycerol and 0.01% thimerosal; pH 7
Gene ARHGAP1
Gene Accession No. Q07960
Gene Alias ARHGAP1; ARHGAP5; B230365D05Rik; C76222; CDC42 GTPase-activating protein; CDC42GAP; GFI2; growth factor independent 2; GTPase-activating protein rhoGAP; GTPase-activating protein rhoOGAP; GTPase-activating protein, Rho, 1; LOC512817 protein; p100 RasGAP-associated p105 protein; p105 RhoGAP; p190-B; p190BRhoGAP; p50rhoGAP; p50-RhoGAP; Rho GTPase activating protein 1; Rho GTPase activating protein 5; rho GTPase-activating protein 1; Rho GTPase-activating protein 5; RHOGAP; RHOGAP1; RHOGAP5; rho-related small GTPase protein activator; Rho-type GTPase-activating protein 1; rho-type GTPase-activating protein 5
Gene Symbols ARHGAP1
Host Species Rabbit
Immunogen Recombinant protein encompassing a sequence within the N-terminus region of human ARHGAP1. The exact sequence is proprietary.
Purification Method Antigen affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 392
Target Species Human
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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