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Invitrogen™ RhoGAP Polyclonal Antibody
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Catalog No. 01675342
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100 μg
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Catalog No. Quantity
01-675-342 100 μg
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Catalog No. 01-675-342 Supplier Invitrogen™ Supplier No. PA141520
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Description

Rabbit Polyclonal Antibody

The amino acid sequence used as immunogen is 88% homologous in chicken.

The p190 RhoGAP protein is associated with p120 RasGAP in growth-factor stimulated and tyrosine kinase transformed cells. It functions as a GTPase - activating protein (GAP) for Rho and Rac family proteins, which are involved in regulating cytoskeletal actin and membrane ruffling. The antibody appears to couple signal transduction via Ras and Rho through its association with RasGAP. The presence of two adjacent SH2 domains in the p21 RAS GAP indicates that GAP might interact directly with tyrosine kinases.
TRUSTED_SUSTAINABILITY

Specifications

Antigen RhoGAP
Applications Western Blot
Classification Polyclonal
Concentration 0.5 mg/mL
Conjugate Unconjugated
Formulation PBS with 0.2% gelatin and 0.05% sodium azide
Gene ARHGAP1
Gene Accession No. Q07960, Q5FWK3
Gene Alias ARHGAP1; ARHGAP5; B230365D05Rik; C76222; CDC42 GTPase-activating protein; CDC42GAP; GFI2; growth factor independent 2; GTPase-activating protein rhoGAP; GTPase-activating protein rhoOGAP; GTPase-activating protein, Rho, 1; LOC512817 protein; p100 RasGAP-associated p105 protein; p105 RhoGAP; p190-B; p190BRhoGAP; p50rhoGAP; p50-RhoGAP; Rho GTPase activating protein 1; Rho GTPase activating protein 5; rho GTPase-activating protein 1; Rho GTPase-activating protein 5; RHOGAP; RHOGAP1; RHOGAP5; rho-related small GTPase protein activator; Rho-type GTPase-activating protein 1; rho-type GTPase-activating protein 5
Gene Symbols ARHGAP1
Host Species Rabbit
Immunogen A portion of amino acids 1-50 of human RhoGAP1.
Purification Method Protein G
Quantity 100 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 228359, 311193, 392, 483631, 512817
Target Species Human, Mouse, Rat, Canine, Monkey, Bovine
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov
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