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Invitrogen™ RhoH Polyclonal Antibody
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Catalog No. PIPA599487
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100 μL
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PIPA599487 100 μL
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Catalog No. PIPA599487 Supplier Invitrogen™ Supplier No. PA599487
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Description

Rabbit Polyclonal Antibody

Antibody detects endogenous levels of total RhoH.

The Rho subfamily of small GTP-binding proteins mediates many fundamental cellular functions. The commonly studied members (Rho, Rac, and CDC42) regulate actin reorganization and affect diverse cellular responses, including adhesion, cytokinesis, and motility. RhoH, also known as TTF (Translocation Three Four), Rho-related GTP-binding protein and ras homolog gene family member H, is unlike most other small G proteins. Most small G proteins are expressed ubiquitously, however, Rho H is expressed only in hemopoietic cells and tissues. Translocations and a high frequency of Rho H mutation have been detected in primary lymphoma cells. Rho H expression has also been observed in activated neutrophils. RhoH is GTPase deficient, remaining in a GTP-bound activated state without cycling. Rho H may be involved in the functional differentiation of T cells and in cytoskeleton organization. The RhoH/TTF (ARHH) gene maps to chromosome 4p13 and encodes a 191 -amino acid polypeptide.
TRUSTED_SUSTAINABILITY

Specifications

Antigen RhoH
Applications Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
Classification Polyclonal
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
Gene RHOH
Gene Accession No. Q15669, Q9D3G9
Gene Alias 5830400A04Rik; ARHH; AU019774; GTP-binding protein TTF; ras homolog family member H; ras homolog gene family, member H; RHOH; rho-related GTP-binding protein RhoH; Translocation three four protein; TTF; TTF, translocation three four
Gene Symbols RHOH
Host Species Rabbit
Immunogen A synthesized peptide derived from human RHOH(Accession Q15669), corresponding to amino acid residues V114-E164.
Purification Method Affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 305341, 399, 74734
Target Species Human, Mouse, Rat
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov
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