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  5. Tocris Bioscience™ Rhosin hydrochloride

Tocris Bioscience™ Rhosin hydrochloride
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Catalog No. 500350R
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50 mg
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Catalog No. Quantity
50-035-0R 50 mg
50-031-0R 10 mg
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Catalog No. 50-035-0R Supplier Tocris Bioscience™ Supplier No. 5003/50
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Description

Rho GTPase inhibitor

Rhosin hydrochloride is a Rho GTPase inhibitor (Kd = 354 nM). Inhibits binding of RhoA to guanine nucleotide exchange factors (GEFs) including LARG, DBL, LBC, p115 RhoGEF and PDZ RhoGEF. Has no effect on the binding of Rac1 or Cdc42 to their respective GEFs. Suppresses RhoA/C-mediated breast cancer cell migration and invasion in vitro. Also induces neurite outgrowth in synergy with NGF.

Specifications

Quantity 50 mg
Product Type Rhosin hydrochloride
Purity >98%
Molecular Weight (g/mol) 394.86
Inhibitors Rho GTPase Inhibitors

For Research Use Only

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