Invitrogen™ Rhotekin Monoclonal Antibody (OTI2E9)

Mouse Monoclonal Antibody

Supplier:  Invitrogen™ MA526050

Catalog No. PIMA526050

Description

Rhotekin Monoclonal Antibody for Western Blot, IHC (P)

This gene encodes a scaffold protein that interacts with GTP-bound Rho proteins. Binding of this protein inhibits the GTPase activity of Rho proteins. This protein may interfere with the conversion of active, GTP-bound Rho to the inactive GDP-bound form by RhoGAP. Rho proteins regulate many important cellular processes, including cytokinesis, transcription, smooth muscle contraction, cell growth and transformation. Dysregulation of the Rho signal transduction pathway has been implicated in many forms of cancer. Alternative splicing results in multiple transcript variants encoding different isoforms.

Specifications

• Antigen: Rhotekin
• Classification: Monoclonal
• Concentration: 1 mg/mL
• Formulation: PBS with 1% BSA, 50% glycerol and 0.02% sodium azide; pH 7.3
• Gene Accession No.: Q9BST9
• Gene Symbols: RTKN
• Immunogen: Full length human recombinant protein of RTKN produced in HEK293T cell.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG2a

• Applications: Immunohistochemistry (Paraffin), Western Blot
• Clone: OTI2E9
• Conjugate: Unconjugated
• Gene: RTKN
• Gene Alias: hypothetical protein LOC539691; RGD:727874}; rhotekin; RTKN; rtkn {ECO:0000312; RTKN1
• Host Species: Mouse
• Purification Method: Affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 6242
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Form: Liquid