Invitrogen™ Rhotekin Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA5112704

Catalog No. PIPA5112704

Description

Rhotekin Polyclonal Antibody for Western Blot, IHC (P), ELISA

This gene encodes a scaffold protein that interacts with GTP-bound Rho proteins. Binding of this protein inhibits the GTPase activity of Rho proteins. This protein may interfere with the conversion of active, GTP-bound Rho to the inactive GDP-bound form by RhoGAP. Rho proteins regulate many important cellular processes, including cytokinesis, transcription, smooth muscle contraction, cell growth and transformation. Dysregulation of the Rho signal transduction pathway has been implicated in many forms of cancer. Alternative splicing results in multiple transcript variants encoding different isoforms.

Specifications

• Antigen: Rhotekin
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: RTKN
• Gene Alias: hypothetical protein LOC539691; RGD:727874}; rhotekin; RTKN; rtkn {ECO:0000312; RTKN1
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 20166, 6242
• Content And Storage: -20°C or -80°C if preferred
• Form: Liquid

• Applications: ELISA, Immunohistochemistry (Paraffin), Western Blot
• Concentration: 0.79 mg/mL
• Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
• Gene Accession No.: Q8C6B2, Q9BST9
• Gene Symbols: RTKN
• Immunogen: Recombinant Human Rhotekin protein (304-563AA).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse
• Product Type: Antibody
• Isotype: IgG

Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov