Promotional price valid on web orders only. Your contract pricing may differ. Interested in signing up for a dedicated account number?
Learn More
  1. Home
  2. Products
  3. Antibodies
  4. Primary Antibodies
  5. All Primary Antibodies
  6. PIPA529931

Invitrogen™ Rhotekin Polyclonal Antibody
GREENER_CHOICE

Catalog No. PIPA529931
Change view
Click to view available options
Quantity:
100 μL
1 product options available for selection
Product selection table with 1 available options. Use arrow keys to navigate and Enter or Space to select.
Catalog No. Quantity
PIPA529931 100 μL
Use arrow keys to navigate between rows. Press Enter or Space to select a product option. 1 options available.
1 options
Catalog No. PIPA529931 Supplier Invitrogen™ Supplier No. PA529931
Only null left
Add to Cart
Add to Cart

Description

Rabbit Polyclonal Antibody

Recommended positive controls: 293T, A431, Jurkat, Raji, mouse brain, NCI-H929, human Rhotekin-transfected 293T. Predicted reactivity: Mouse (93%), Rat (96%), Rhesus Monkey (99%), Bovine (94%). Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.

This gene encodes a scaffold protein that interacts with GTP-bound Rho proteins. Binding of this protein inhibits the GTPase activity of Rho proteins. This protein may interfere with the conversion of active, GTP-bound Rho to the inactive GDP-bound form by RhoGAP. Rho proteins regulate many important cellular processes, including cytokinesis, transcription, smooth muscle contraction, cell growth and transformation. Dysregulation of the Rho signal transduction pathway has been implicated in many forms of cancer. Alternative splicing results in multiple transcript variants encoding different isoforms.
TRUSTED_SUSTAINABILITY

Specifications

Antigen Rhotekin
Applications Western Blot, Immunocytochemistry
Classification Polyclonal
Concentration 0.54 mg/mL
Conjugate Unconjugated
Formulation 0.1M tris glycine with 20% glycerol and 0.01% thimerosal; pH 7
Gene RTKN
Gene Accession No. Q8C6B2, Q9BST9
Gene Alias hypothetical protein LOC539691; RGD:727874}; rhotekin; RTKN; rtkn {ECO:0000312; RTKN1
Gene Symbols RTKN
Host Species Rabbit
Immunogen Recombinant protein encompassing a sequence within the N-terminus region of human Rhotekin. The exact sequence is proprietary.
Purification Method Antigen affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 20166, 6242
Target Species Human, Mouse
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
Show More Show Less

Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov
Product Title
Select an issue

By clicking Submit, you acknowledge that you may be contacted by Fisher Scientific in regards to the feedback you have provided in this form. We will not share your information for any other purposes. All contact information provided shall also be maintained in accordance with our Privacy Policy.