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Tocris Bioscience™ Ribavirin
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Catalog No. 450150
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50 mg
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45-015-0 50 mg
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Catalog No. 45-015-0 Supplier Tocris Bioscience™ Supplier No. 4501/50
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Description

Serine protease inhibitor; inhibits tryptase

Antiviral guanosine ribonucleoside analog; misincorporated into mRNA by viral-dependent RNA polymerases. Binds to and redistributes mammalian eIF4E from the nucleus to the cytoplasm (Ki ∽ 0.3 μM for the active metabolite, ribavirin triphosphate). Also inosine monophosphate dehydrogenase (IMPDH) inhibitor. Represses colony formation of primary AML-M5 progenitor cells (IC50 ∽ 1 μM); reduces disease severity in acute myeloid leukemia (AML). Inhibits cytopathic effect of SARS-CoV in Vero cells in vitro. Orally available.

Chemical Identifiers

CAS 36791-04-5
Molecular Formula C8H12N4O5

Specifications

Quantity 50 mg
Formula Weight 244.2
Purity >99%
Molecular Weight (g/mol) 244.207
Chemical Name or Material Protein-synthesizing GTPase Compounds

Safety and Handling

Recommended Storage Store at +4°C
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