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Ribavirin, Tocris Bioscience™

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Quantity:
50mg
This item is not returnable. View return policy
36791-04-5
C8H12N4O5
244.207
IWUCXVSUMQZMFG-AFCXAGJDSA-N
ribavirin,tribavirin,virazole,rebetol,ribavirine,copegus,vilona,ribamide,ribamidil,ribasphere
37542
CHEBI:63580
1-[(2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-1,2,4-triazole-3-carboxamide
C1=NC(=NN1C2C(C(C(O2)CO)O)O)C(=O)N
This item is not returnable. View return policy
36791-04-5
C8H12N4O5
244.207
IWUCXVSUMQZMFG-AFCXAGJDSA-N
ribavirin,tribavirin,virazole,rebetol,ribavirine,copegus,vilona,ribamide,ribamidil,ribasphere
37542
CHEBI:63580
1-[(2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-1,2,4-triazole-3-carboxamide
C1=NC(=NN1C2C(C(C(O2)CO)O)O)C(=O)N

Antiviral guanosine analog; blocks eIF4E activity

Antiviral guanosine ribonucleoside analog; misincorporated into mRNA by viral-dependent RNA polymerases. Binds to and redistributes mammalian eIF4E from the nucleus to the cytoplasm (Ki ∽ 0.3 μM for the active metabolite, ribavirin triphosphate). Represses colony formation of primary AML-M5 progenitor cells (IC50 ∽ 1 μM); reduces disease severity in acute myeloid leukemia (AML). Orally available.
Quantity 50mg
Formula Weight 244.2
Percent Purity >99%
Chemical Name or Material Protein-synthesizing GTPase Compounds

Recommended Storage : Store at +4°C