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Ribonuclease T2 Rabbit anti-Human, Polyclonal, Bioss
SDP

Catalog No. 501986942
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50-198-6942 100 μL
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Catalog No. 50-198-6942 Supplier Bioss Supplier No. BS5972R
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Description

Rabbit Polyclonal Antibody

RNASET2 is a novel member of the Rh/T2/S-glycoprotein class of extracellular ribonucleases. It is a single copy gene that maps to 6q27, a region associated with human malignancies and chromosomal rearrangement, and has been suggested to function as a tumor suppressor protein. Its expression is suppressed in Human T-cell Leukemia Virus type 1 (HTLV-1) infected cells following the binding of the HTLV-1 Tax protein to the RNASET2 promoter. As Adult T-cell leukemia (ATL) is one of the primary diseases caused by HTLV-1 infection, a reduction in the level of RNASET2 by Tax may play a role in ATL development.

Specifications

Antigen Ribonuclease T2
Applications Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot
Classification Polyclonal
Concentration 1 μg/mL
Conjugate Unconjugated
Formulation PBS with 1% BSA, 50% glycerol and 0.09% sodium azide; pH
Gene RNASET2
Gene Accession No. O00584
Gene Alias 0610007O07Rik; 4833423A10Rik; 4930532K22Rik; bA514O12.3; C79750; Ribonuclease 6; Ribonuclease 6-A; Ribonuclease 6-B; Ribonuclease T2; ribonuclease T2A; Ribonuclease T2-A; Ribonuclease T2-B; RNase T2; Rnase6pl; RNASET2; Rnaset2a; Rnaset2b; RP11-514O12.3
Gene Symbols RNASET2
Host Species Rabbit
Immunogen KLH conjugated synthetic peptide derived from human Ribonuclease T2.
Purification Method Protein A
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 8635
Target Species Human
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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