Invitrogen™ Ribophorin I Monoclonal Antibody (4B1-1E6)

Mouse Monoclonal Antibody

Supplier:  Invitrogen™ MA519852

Catalog No. PIMA519852

Description

Peptide Sequence: ASSEAPPLIN EDVKRTVDLS SHLAKVTAEV VLAHLGGGST SRATSFLLAL EPELEARLAH LGVQVKGEDE EENNLEVRET KIKGKSGRFF TVKLPVALDP GAKISVIVET VYTHVLHPYP TQITQSEKQF VVFEGNHYFY SPYPTKTQTM RVKLASRNVE SYTKLGNPTR SEDLLDYGPF RDVPAYSQDT FKVHYENNSP FLTITSMTRV IEVSHWGNIA VEENVDLKHT GAVLKGPFSR YDYQRQPDSG ISSIRSFKTI LPAAAQDVYY RDEIGNVSTS HLLILDDSVE MEIRPRFPLF GGWKTHYIVG YNLPSYEYLY NLGDQYALKM RFVDHVFDEQ VIDSLTVKII LPEGAKNIEI DSPYEISRAP DELHYTYLDT SGRPVIVAYK KNLVEQHIQD IVVHYTFNKV LMLQEPLLVV AAFYILFFTV IIYVRLDFSI TKDPAAEARM KVACITEQVL TLVNKRIGLY RHFDETVNRY KQSRDISTLN SGKKSLEAEH KALTSEIALL QSRLKTEGSD LCDRVSEMQK LDAQVKELVL KSAVEAERLV AGKLKKDTYI ENEKLISGKR QELVTKIDHI LDAL.

Ribophorins 1 and 2 are abundant and highly conserved glycoproteins residing in the endoplasic reticulum, that participate in ribosome binding. Mammalian oligosaccharyltransferase activity is associated with a protein complex composed of RPN1, RPN2, and an oligosaccharyltransferase protein. RPN1 is a component of the proteasome base. The ubiquitin-like (UBL) domain of recombinant Rad23 interacts with proteasomes through the leucine-rich repeat domain of RPN1. The RPN1 gene maps to chromosome 3 in somatic cell hybrids, and the RPN2 gene maps to chromosome 20 by in situ hybridization.

Specifications

• Antigen: Ribophorin I
• Classification: Monoclonal
• Concentration: 1.0 mg/mL
• Formulation: PBS with no preservative; pH 7.4
• Gene Accession No.: P04843
• Gene Symbols: RPN1
• Immunogen: RPN1 (AAH10839, 24 a.a. ~ 607 a.a) full-length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
• Quantity: 100 μg
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG1 κ

• Applications: ELISA, Immunocytochemistry
• Clone: 4B1-1E6
• Conjugate: Unconjugated
• Gene: RPN1
• Gene Alias: AU018702; D6Wsu137e; Dolichyl-diphosphooligosaccharide--protein; dolichyl-diphosphooligosaccharide-protein glycosyltransferase 67 kDa subunit; dolichyl-diphosphooligosaccharide--protein glycosyltransferase 67 kDa subunit; Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 1; oligosaccharyltransfe; oligosaccharyltransferase 1 homolog; oligosaccharyltransferase complex subunit (non-catalytic); OST1; QccE-21639; QtsA-18349; RBPH1; RIBI; ribophorin I; Ribophorin-1; RPN1; Rpn-1; RPN-I; unnamed protein product
• Host Species: Mouse
• Purification Method: Affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 6184
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Form: Liquid