Invitrogen™ Ribophorin I Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA588589

Catalog No. PIPA588589

Description

Immunogen sequence: APGSASSEAP PLINEDVKRT VDLSSHLAKV TAEVVLAHLG GGSTSRATSF LLALEPELEA RLAHLGVQVK GEDEEENNLE VRETKIKGKS GRFFTVKLPV ALDPGAKISV IVETVYTHVL HPYPTQITQS EKQFVVFEGN HYFYSPYPTK TQTMRVKLAS RNVESYTKLG NPTRSEDLLD YGPFRDVPAY SQDTFKVHYE NNSPFLTITS MTRVIEVSHW GNIAVEENVD LKHTGAVLKG PFSRYDYQRQ PDSGISSIRS F; Positive Samples: HL-60, HepG2, SKOV3, MCF7, BxPC-3, Mouse liver, Rat liver; Cellular Location: Endoplasmic reticulum membrane, Melanosome, Single-pass type I membrane protein.

Ribophorins 1 and 2 are abundant and highly conserved glycoproteins residing in the endoplasic reticulum, that participate in ribosome binding. Mammalian oligosaccharyltransferase activity is associated with a protein complex composed of RPN1, RPN2, and an oligosaccharyltransferase protein. RPN1 is a component of the proteasome base. The ubiquitin-like (UBL) domain of recombinant Rad23 interacts with proteasomes through the leucine-rich repeat domain of RPN1. The RPN1 gene maps to chromosome 3 in somatic cell hybrids, and the RPN2 gene maps to chromosome 20 by in situ hybridization.

Specifications

• Antigen: Ribophorin I
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: RPN1
• Gene Alias: AU018702; D6Wsu137e; Dolichyl-diphosphooligosaccharide--protein; dolichyl-diphosphooligosaccharide-protein glycosyltransferase 67 kDa subunit; dolichyl-diphosphooligosaccharide--protein glycosyltransferase 67 kDa subunit; Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 1; oligosaccharyltransfe; oligosaccharyltransferase 1 homolog; oligosaccharyltransferase complex subunit (non-catalytic); OST1; QccE-21639; QtsA-18349; RBPH1; RIBI; ribophorin I; Ribophorin-1; RPN1; Rpn-1; RPN-I; unnamed protein product
• Host Species: Rabbit
• Purification Method: Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 103963, 25596, 6184
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Form: Liquid

• Applications: ELISA, Immunohistochemistry (Paraffin), Western Blot
• Concentration: 0.19 mg/mL
• Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
• Gene Accession No.: P04843, P07153, Q91YQ5
• Gene Symbols: RPN1
• Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 20-280 of human RPN1 (NP_0029411).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rat
• Product Type: Antibody
• Isotype: IgG

Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov