Ric-8A Rabbit anti-Human, Polyclonal, Bethyl Laboratories

Rabbit Polyclonal Antibody

Supplier:  Bethyl Laboratories, Inc A304571AT

Catalog No. 50-156-8073

Description

The recommended shelf life for this product is 1 year from date of receipt.

Guanine nucleotide exchange factor (GEF), which can activate some, but not all, G-alpha proteins. Able to activate GNAI1, GNAO1 and GNAQ, but not GNAS by exchanging bound GDP for free GTP. Involved in regulation of microtubule pulling forces during mitotic movement of chromosomes by stimulating G(i)-alpha protein, possibly leading to release G(i)-alpha-GTP and NuMA proteins from the NuMA-GPSM2-G(i)-alpha-GDP complex. Also acts as an activator for G(q)-alpha (GNAQ) protein by enhancing the G(q)-coupled receptor-mediated ERK activation.

Specifications

• Antigen: Ric-8A
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: RIC8A
• Gene Alias: RIC8A; synembryn; resistance to inhibitors of cholinesterase 8 homolog A (C. elegans); MGC104517; MGC131931; RIC8; RIC8 protein; resistance to inhibitors of cholinesterase 8 homolog A; MGC148073; MGC148074
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 60626
• Content And Storage: 4° C
• Form: Liquid

• Applications: Immunoprecipitation
• Concentration: 1 mg/ml
• Formulation: phosphate, tris citrate with 0.09% sodium azide; pH 7-8
• Gene Accession No.: Q9NPQ8
• Gene Symbols: RIC8A
• Immunogen: Between 1 and 50
• Quantity: 10 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG