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RIC8A Monoclonal Antibody (OTI3G3), TrueMAB™, OriGene
SDP

Catalog No. 501672198
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Catalog No. Quantity
50-167-2198 100 μL
50-254-2570 30 μL
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Catalog No. 50-167-2198 Supplier OriGene Supplier No. TA501055
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Description

Mouse Monoclonal Antibody

Guanine nucleotide exchange factor (GEF), which can activate some, but not all, G-alpha proteins. Able to activate GNAI1, GNAO1 and GNAQ, but not GNAS by exchanging bound GDP for free GTP. Involved in regulation of microtubule pulling forces during mitotic movement of chromosomes by stimulating G(i)-alpha protein, possibly leading to release G(i)-alpha-GTP and NuMA proteins from the NuMA-GPSM2-G(i)-alpha-GDP complex. Also acts as an activator for G(q)-alpha (GNAQ) protein by enhancing the G(q)-coupled receptor-mediated ERK activation.

Specifications

Antigen RIC8A
Applications Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot
Classification Monoclonal
Clone OTI3G3
Concentration 0.83 mg/mL
Conjugate Unconjugated
Formulation PBS with 1% BSA, 50% glycerol and 0.02% sodium azide
Gene RIC8A
Gene Accession No. Q9NPQ8
Gene Alias RIC8
Gene Symbols RIC8A
Host Species Mouse
Immunogen Full length human recombit protein of human RIC8A produced in HEK293T cell.
Purification Method Affinity Chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 60626
Target Species Human
Content And Storage -20° C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Liquid
Isotype IgG1
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