RIC8A Mouse anti-Human, Clone: OTI3G3, lyophilized, TrueMAB™

Mouse Monoclonal Antibody

Supplier:  OriGene CF501055

Catalog No. 50-166-0093

Description

Reconstitute with PBS (pH 7.3) and recommend to perform another round of desalting process using Product No. 7KMWCO

Guanine nucleotide exchange factor (GEF), which can activate some, but not all, G-alpha proteins. Able to activate GNAI1, GNAO1 and GNAQ, but not GNAS by exchanging bound GDP for free GTP. Involved in regulation of microtubule pulling forces during mitotic movement of chromosomes by stimulating G(i)-alpha protein, possibly leading to release G(i)-alpha-GTP and NuMA proteins from the NuMA-GPSM2-G(i)-alpha-GDP complex. Also acts as an activator for G(q)-alpha (GNAQ) protein by enhancing the G(q)-coupled receptor-mediated ERK activation.

Specifications

• Antigen: RIC8A
• Classification: Monoclonal
• Conjugate: Unconjugated
• Gene: RIC8A
• Gene Alias: RIC8
• Host Species: Mouse
• Purification Method: Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 60626
• Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
• Form: Lyophilized

• Applications: Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot
• Clone: OTI3G3
• Formulation: PBS with 8% trehalose and no preservative; pH 7.3
• Gene Accession No.: Q9NPQ8
• Gene Symbols: RIC8A
• Immunogen: Full length human recombit protein of human RIC8A produced in HEK293T cell.
• Quantity: 100 μg
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG1