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RIC8A Mouse anti-Human, Clone: OTI3G3, lyophilized, TrueMAB™

Mouse Monoclonal Antibody
Supplier: OriGene CF501055

Description
Reconstitute with PBS (pH 7.3) and recommend to perform another round of desalting process using Product No. 7KMWCO
Guanine nucleotide exchange factor (GEF), which can activate some, but not all, G-alpha proteins. Able to activate GNAI1, GNAO1 and GNAQ, but not GNAS by exchanging bound GDP for free GTP. Involved in regulation of microtubule pulling forces during mitotic movement of chromosomes by stimulating G(i)-alpha protein, possibly leading to release G(i)-alpha-GTP and NuMA proteins from the NuMA-GPSM2-G(i)-alpha-GDP complex. Also acts as an activator for G(q)-alpha (GNAQ) protein by enhancing the G(q)-coupled receptor-mediated ERK activation.Specifications
RIC8A | |
Monoclonal | |
Unconjugated | |
RIC8A | |
RIC8 | |
Mouse | |
Affinity Chromatography | |
RUO | |
60626 | |
-20° C, Avoid Freeze/Thaw Cycles | |
Lyophilized |
Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot | |
OTI3G3 | |
PBS with 8% trehalose and no preservative; pH 7.3 | |
Q9NPQ8 | |
RIC8A | |
Full length human recombit protein of human RIC8A produced in HEK293T cell. | |
100 μg | |
Primary | |
Human | |
Antibody | |
IgG1 |
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