Promotional price valid on web orders only. Your contract pricing may differ. Interested in signing up for a dedicated account number?
Learn More
  1. Home
  2. Products
  3. Antibodies
  4. Primary Antibodies
  5. All Primary Antibodies
  6. PIPA5100318

Invitrogen™ RIC8A Polyclonal Antibody
GREENER_CHOICE

Catalog No. PIPA5100318
Change view
Click to view available options
Quantity:
100 μL
1 product options available for selection
Product selection table with 1 available options. Use arrow keys to navigate and Enter or Space to select.
Catalog No. Quantity
PIPA5100318 100 μL
Use arrow keys to navigate between rows. Press Enter or Space to select a product option. 1 options available.
1 options
Catalog No. PIPA5100318 Supplier Invitrogen™ Supplier No. PA5100318
Only null left
Add to Cart
Add to Cart

Description

Rabbit Polyclonal Antibody

Antibody detects endogenous levels of total RIC8A.

Guanine nucleotide exchange factor (GEF), which can activate some, but not all, G-alpha proteins. Able to activate GNAI1, GNAO1 and GNAQ, but not GNAS by exchanging bound GDP for free GTP. Involved in regulation of microtubule pulling forces during mitotic movement of chromosomes by stimulating G(i)-alpha protein, possibly leading to release G(i)-alpha-GTP and NuMA proteins from the NuMA-GPSM2-G(i)-alpha-GDP complex. Also acts as an activator for G(q)-alpha (GNAQ) protein by enhancing the G(q)-coupled receptor-mediated ERK activation.
TRUSTED_SUSTAINABILITY

Specifications

Antigen RIC8A
Applications Immunohistochemistry (Paraffin), Western Blot
Classification Polyclonal
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
Gene RIC8A
Gene Accession No. Q3TIR3, Q80ZG1, Q9NPQ8
Gene Alias AI114950; heterotrimeric G protein guanine nucleotide exchange factor Ric-8A; MGC104517; MGC131931; MGC148073; MGC148074; Protein Ric-8A; resistance to inhibitors of cholinesterase 8 homolog; resistance to inhibitors of cholinesterase 8 homolog (C. elegans); resistance to inhibitors of cholinesterase 8 homolog A; resistance to inhibitors of cholinesterase 8A; Ric8; RIC-8; RIC8 guanine nucleotide exchange factor A; RIC8 protein; Ric8a; Ric-8A; synembryn; synembryn-A
Gene Symbols RIC8A
Host Species Rabbit
Immunogen A synthesized peptide derived from human RIC8A(Accession Q9NPQ8), corresponding to amino acid residues K476-P526.
Purification Method Affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 101489, 293614, 60626
Target Species Human, Mouse, Rat
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG
Show More Show Less

Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov
Product Title
Select an issue

By clicking Submit, you acknowledge that you may be contacted by Fisher Scientific in regards to the feedback you have provided in this form. We will not share your information for any other purposes. All contact information provided shall also be maintained in accordance with our Privacy Policy.