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RIC8A Rabbit anti-Human, Polyclonal, Bioss
SDP

Catalog No. 501981294
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50-198-1294 100 μL
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Catalog No. 50-198-1294 Supplier Bioss Supplier No. BS11355R
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Description

Rabbit Polyclonal Antibody

Guanine nucleotide exchange factor (GEF), which can activate some, but not all, G-alpha proteins. Able to activate GNAI1, GNAO1 and GNAQ, but not GNAS by exchanging bound GDP for free GTP. Involved in regulation of microtubule pulling forces during mitotic movement of chromosomes by stimulating G(i)-alpha protein, possibly leading to release G(i)-alpha-GTP and NuMA proteins from the NuMA-GPSM2-G(i)-alpha-GDP complex. Also acts as an activator for G(q)-alpha (GNAQ) protein by enhancing the G(q)-coupled receptor-mediated ERK activation.

Specifications

Antigen RIC8A
Applications Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot
Classification Polyclonal
Concentration 1 μg/mL
Conjugate Unconjugated
Formulation PBS with 1% BSA, 50% glycerol and 0.09% sodium azide; pH
Gene RIC8A
Gene Accession No. Q9NPQ8
Gene Alias AI114950; heterotrimeric G protein guanine nucleotide exchange factor Ric-8A; MGC104517; MGC131931; MGC148073; MGC148074; Protein Ric-8A; resistance to inhibitors of cholinesterase 8 homolog; resistance to inhibitors of cholinesterase 8 homolog (C. elegans); resistance to inhibitors of cholinesterase 8 homolog A; resistance to inhibitors of cholinesterase 8A; Ric8; RIC-8; RIC8 guanine nucleotide exchange factor A; RIC8 protein; Ric8a; Ric-8A; synembryn; Synembryn-A
Gene Symbols RIC8A
Host Species Rabbit
Immunogen KLH conjugated synthetic peptide derived from human RIC8A.
Purification Method Protein A
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 60626
Target Species Human
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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