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Invitrogen™ RILPL1 Polyclonal Antibody
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Catalog No. PIPA559512
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100 μL
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PIPA559512 100 μL
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Catalog No. PIPA559512 Supplier Invitrogen™ Supplier No. PA559512
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Description

Rabbit Polyclonal Antibody

Immunogen sequence: LELDRLRLER MDRIEKERKH QKELELVEDV WRGEAQDLLS QIAQLQEENK QLMTNLSHKD VNFSEEEFQK HEGMSERERQ VMKKLKEV Highest antigen sequence identity to the following orthologs: Mouse - 94%, Rat - 94%.

Plays a role in the regulation of cell shape and polarity. Plays a role in cellular protein transport, including protein transport away from primary cilia. Neuroprotective protein, which acts by sequestring GAPDH in the cytosol and prevent the apoptotic function of GAPDH in the nucleus. Competes with SIAH1 for binding GAPDH. Does not regulate lysosomal morphology and distribution (PubMed:14668488). Binds to RAB10 following LRRK2-mediated RAB10 phosphorylation which leads to inhibition of ciliogenesis (PubMed:30398148). [UniProt].
TRUSTED_SUSTAINABILITY

Specifications

Antigen RILPL1
Applications Immunohistochemistry (Paraffin), Immunocytochemistry
Classification Polyclonal
Concentration 0.3 mg/mL
Conjugate Unconjugated
Formulation PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
Gene RILPL1
Gene Accession No. Q5EBL4
Gene Alias 2900002H16Rik; 6330559I19Rik; GAPDH competitor of SIAH protein enhances life; GAPDH's competitor of SIAH1 protein enhances life; GOSPEL; MNCb-2440; Rab interacting lysosomal protein like 1; Rab interacting lysosomal protein-like 1; rab-interacting lysosomal-like protein 1; RGD1307973; Rilpl1; RILP-like protein 1; RLP1
Gene Symbols RILPL1
Host Species Rabbit
Immunogen Recombinant protein corresponding to Human RILPL1. Recombinant protein control fragment (Product #RP-97878).
Purification Method Antigen affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 353116
Target Species Human
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov
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