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RIM1/ABCA4 Rabbit anti-Human, Polyclonal, Bioss
SDP

Catalog No. 501981295
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50-198-1295 100 μL
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Catalog No. 50-198-1295 Supplier Bioss Supplier No. BS11356R
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Description

Rabbit Polyclonal Antibody

Rims1 is a RAS gene superfamily member that regulates synaptic vesicle exocytosis. Rims1 also plays a role in the regulation of voltage-gated calcium channels during neurotransmitter and insulin release. Mutations in the Rims1 gene have suggested a role cognition and have been identified as the cause of cone-rod dystrophy type 7. Further, Rims1 may act as scaffold protein that regulates neurotransmitter release at the active zone. Rims1 may also be essential for maintaining normal probability of neurotransmitter release and for regulating release during short-term synaptic plasticity. Rims1 also plays a role in dendrite formation by melanocytes. Multiple transcript variants encoding different isoforms have been described for this Rims1. Diseases associated with RIMS1 include Cone-Rod Dystrophy 7 and Retinitis Pigmentosa.

Specifications

Antigen RIM1/ABCA4
Applications Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot
Classification Polyclonal
Concentration 1 μg/mL
Conjugate Unconjugated
Formulation PBS with 1% BSA, 50% glycerol and 0.09% sodium azide; pH
Gene Rims1
Gene Accession No. Q86UR5
Gene Alias C030033M19Rik; CORD7; Kiaa0340; mKIAA0340; Nbla00761; Rab3 effector; Rab3 interacting protein 1; Rab-3-interacting molecule 1; rab3-interacting molecule 1; Rab-3-interacting protein 1; rab3-interacting protein 1; Rab-3-interacting protein 2; RAB3-interacting protein 2; Rab3ip1; RAB3IP2; regulating synaptic membrane exocytosis 1; regulating synaptic membrane exocytosis 1 beta; Regulating synaptic membrane exocytosis protein 1; Rim; RIM 1; RIM1; RIM1a; RIM1alpha; Rim1b protein; RIMS1; Serg1; synaptic exocytosis regulator 1
Gene Symbols Rims1
Host Species Rabbit
Immunogen KLH conjugated synthetic peptide derived from human RIM1.
Purification Method Protein A
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 22999
Target Species Human
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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