Invitrogen™ RIMBP2 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA560614

Catalog No. PIPA560614

Description

Immunogen sequence: RVDNITQISA QLSWLPTNSN YSHVIFLNEE EFDIVKAARY KYQFFNLRPN MAYKVKVLAK PHQMPWQLPL EQREKKEAFV EFSTLP Highest antigen sequence identity to the following orthologs: Mouse - 95%, Rat - 95%.

The presynaptic active zone mediates synaptic vesicle exocytosis at a synapse. RIM proteins are active zone scaffolding molecules that--among others--mediate vesicle priming and directly or indirectly interact with most other essential presynaptic proteins. RIMBP2 encodes RIMS-binding protein 2 belonging to RIMBP family. RIMBP2 is supposed to be localized at cell membrane especially synaptic plasma membrane. By interacting with RIMS1, RIMS2, CACNA1D and CACNA1B via the SH3 domains, RIMBP2 mediates synaptic transmission as bifunctional linker.

Specifications

• Antigen: RIMBP2
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: Rimbp2
• Gene Alias: A930033C01Rik; KIAA0318; mKIAA0318; PPP1R133; protein phosphatase 1, regulatory subunit 133; RBP2; RIM binding protein 2; RIMBP2; RIM-BP2; RIMS binding protein 2; RIMS-binding protein 2
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 23504
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Immunohistochemistry (Paraffin)
• Concentration: 0.05 mg/mL
• Formulation: PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
• Gene Accession No.: O15034
• Gene Symbols: Rimbp2
• Immunogen: Recombinant protein corresponding to Human RIMBP2. Recombinant protein control fragment (Product #RP-97658).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG