Invitrogen™ RING1 Recombinant Rabbit Monoclonal Antibody (2Q8D5)

Rabbit Recombinant Monoclonal Antibody

Supplier:  Invitrogen™ MA537980

Catalog No. PIMA537980

Description

Positive Samples: HeLa, HCT116 Immunogen sequence: DPNFDALISK IYPSREEYEA HQDRVLIRLS RLHNQQALSS SIEEGLRMQA MHRAQRVRRP IPGSDQTTTM SGGEGEPGEG EGDGEDVSSD SAPDSAPGPA P.

This gene belongs to the RING finger family, members of which encode proteins characterized by a RING domain, a zinc-binding motif related to the zinc finger domain. The gene product can bind DNA and can act as a transcriptional repressor. It is associated with the multimeric polycomb group protein complex. The gene product interacts with the polycomb group proteins BMI1, EDR1, and CBX4, and colocalizes with these proteins in large nuclear domains. It interacts with the CBX4 protein via its glycine-rich C-terminal domain. The gene maps to the HLA class II region, where it is contiguous with the RING finger genes FABGL and HKE4.

Specifications

• Antigen: RING1
• Classification: Recombinant Monoclonal
• Concentration: 0.4 mg/mL
• Formulation: PBS with 0.05% BSA, 50% glycerol and 0.02% sodium azide; pH 7.3
• Gene Accession No.: Q06587
• Gene Symbols: RING1
• Immunogen: A synthetic peptide corresponding to a sequence within amino acids 100-200 of human RING1A A (Q06587).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG

• Applications: ELISA, Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot
• Clone: 2Q8D5
• Conjugate: Unconjugated
• Gene: RING1
• Gene Alias: E3 ubiquitin-protein ligase RING1; Polycomb complex protein RING1; really interesting new gene 1 protein; RING finger protein 1; RING1; Ring1A; RING-type E3 ubiquitin transferase RING1; Rnf1; Transcription repressor Ring1A
• Host Species: Rabbit
• Purification Method: Affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 6015
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Form: Liquid

Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov