Invitrogen™ RIOK3 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA528585

Catalog No. PIPA528585

Description

Recommended positive controls: 293T, HepG2, Neuro2A, C8D30, NIH-3T3, Raw264.7, C2C12, PC-12, Rat2. Predicted reactivity: Mouse (94%), Rat (94%), Bovine (96%). Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.

The phosphorylation and dephosphorylation of proteins on serine and threonine residues is an essential means of regulating a broad range of cellular functions in eukaryotes, including cell division, homeostasis and apoptosis. A group of proteins that are intimately involved in this process are the serine/threonine (Ser/Thr) protein kinases. SUDD, also known as RIOK3 (RIO kinase 3), is a 519 amino acid protein that contains one protein kinase domain and belongs to the Ser/Thr protein kinase family. Expressed in a variety of tissues, SUDD catayzes the ATP-dependent phosphorylation of target proteins, thereby influencing signaling events throughout the cell. SUDD is expressed as two isoforms due to alternative splicing events.

Specifications

• Antigen: RIOK3
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: RIOK3
• Gene Alias: 1200013N13Rik; D18Ertd331e; E130306C24Rik; homolog of the Aspergillus nidulans sudD gene product; RIO kinase 3; RIOK3; Serine/threonine-protein kinase RIO3; SUDD; sudD (suppressor of bimD6, Aspergillus nidulans) homolog; sudD homolog; sudD suppressor of Aspergillus nidulans bimD6 homolog; sudD suppressor of bimD6 homolog; sudD, suppressor of bimD6 homolog; testicular secretory protein Li 47
• Host Species: Rabbit
• Purification Method: Antigen Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 361293, 66878, 8780
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Immunohistochemistry (Paraffin), Western Blot
• Concentration: 1 mg/mL
• Formulation: PBS with 1% BSA, 20% glycerol and 0.01% thimerosal; pH 7
• Gene Accession No.: O14730, Q9DBU3
• Gene Symbols: RIOK3
• Immunogen: Recombinant fragment corresponding to a region within amino acids 1 and 267 of Human RIOK3.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rat
• Product Type: Antibody
• Isotype: IgG

Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov