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RIOK3 Rabbit anti-Human, Mouse, Rat, Polyclonal, Proteintech
SDP

Catalog No. 501728860 Shop All Proteintech Group Inc Products
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50-172-8860 150 μL
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Catalog No. 50-172-8860 Supplier Proteintech Group Inc Supplier No. 135931AP150UL
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Rabbit Polyclonal Antibody

BCL-10 is an N-terminal CARD (Caspase Recruitment Domain) containing protein that is involved in the adaptive immune response. It promotes apoptosis, pro-caspase-9 maturation, and activation of NF-kappa-B via NIK and IKK. BCL-10 is also an adapter protein between upstream TNFR1-TRADD-RIP complex and the downstream NIK-IKK-IKAP complex. It is a substrate for MALT1. Mutations in the gene can lead to Immmunodeficiency 37 or Lymphoma, mucosa-associated lymphoid type.

Specifications

Antigen RIOK3
Applications Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot
Classification Polyclonal
Concentration 0.15 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
Gene RIOK3
Gene Accession No. O14730, Q9DBU3
Gene Alias RIO kinase 3, RIO kinase 3 (yeast), RIOK3, SUDD, sudD homolog
Gene Symbols Riok3
Host Species Rabbit
Immunogen RIOK3 Fusion Protein Ag4497
Purification Method Antigen Affinity Chromatography
Quantity 150 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 361293, 66878, 8780
Target Species Human, Mouse, Rat
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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