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Invitrogen™ RISC Polyclonal Antibody
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Catalog No. 01675587
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200 μL
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Catalog No. Quantity
01-675-587 200 μL
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Catalog No. 01-675-587 Supplier Invitrogen™ Supplier No. PA141233
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Description

Rabbit Polyclonal Antibody

Suggested positive control: human heart tissue, human heart protein.

The RNA-induced silencing complex (RISC) is a key player in the regulation of gene expression through RNA interference (RNAi) mechanisms. It operates by utilizing small RNA molecules-such as microRNAs (miRNAs), small interfering RNAs (siRNAs), and PIWI-interacting RNAs (piRNAs)-which are processed from double-stranded RNA precursors by enzymes like Drosha and Dicer in animals, and DICER-LIKE in plants. RISC is a versatile molecular complex consisting of Argonaute proteins as its core component, which guides the complex to the target RNA by complementary base pairing. Once assembled, RISC can recruit other proteins that mediate gene silencing by degrading or inhibiting the translation of the target RNA. This post-transcriptional regulation system is integral to numerous biological processes, allowing cells to control gene expression finely and respond to endogenous and exogenous signals. The functionality of RISC in gene silencing highlights its significance in the broader context of genetic regulation and has implications in therapies that target gene expression through RNAi.
TRUSTED_SUSTAINABILITY

Specifications

Antigen RISC
Applications Western Blot
Classification Polyclonal
Concentration 0.5 mg/mL
Conjugate Unconjugated
Formulation PBS with 0.02% sodium azide
Gene SCPEP1
Gene Accession No. Q920A5, Q920A6, Q9HB40
Gene Alias 2410018F01Rik; 4833411K15Rik; AI957256; HSCP1; MSTP034; retinoid inducible serine carboxypeptidase; retinoid-inducible serine carboxypeptidase; retinoid-inducible serine caroboxypeptidase; retinoid-inducible serine caroboxypetidase; Risc; SCP1; SCPEP1; Serine carboxypeptidase 1; serine carboxypeptidase 1 precursor protein; serine caroboxypeptidase 1; UNQ265/PRO302
Gene Symbols SCPEP1
Host Species Rabbit
Immunogen Synthetic peptide corresponding to aa 28-43 of human RISC.
Purification Method Protein G
Quantity 200 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 114861, 59342, 74617
Target Species Human, Mouse, Rat
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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