Invitrogen™ RIT2 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA571336

Catalog No. PIPA571336

Description

RIT2 Polyclonal Antibody for Western Blot

Ras-like without CAAX 2 (RIT2) is a gene located on chromosome 18q12.1, encoding a member of the Ras superfamily of small GTPases. RIT2 is primarily expressed in neuronal tissues, where it plays a crucial role in intracellular signaling pathways that regulate neuronal differentiation, survival, and plasticity. Functionally, RIT2 is involved in neurotrophic factor signaling, contributing to the maintenance and function of the nervous system. This protein interacts with various downstream effectors to influence cellular processes such as growth factor response and neuronal signaling dynamics. Alterations or mutations in RIT2 have been associated with neurological disorders, including Parkinson's disease, implicating its role in neurodegenerative processes. Research into RIT2 aims to elucidate its precise mechanisms in neural signaling and its potential as a therapeutic target for treating neurodegenerative diseases.

Specifications

• Antigen: RIT2
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: RIT2
• Gene Alias: GTP-binding protein Rit2; GTP-binding protein Roc2; Ras like without CAAX 2; RAS-like protein expressed in neuron; ras-like protein expressed in neurons; Ras-like without CAAX 1; Ras-like without CAAX 2; ras-like without CAAX protein 2; RIBA; Ric-like, expressed in neurons; RIN; Rit1; RIT2; ROC2
• Host Species: Rabbit
• Purification Method: Affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 6014
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Form: Liquid

• Applications: Western Blot
• Concentration: 0.5 mg/mL
• Formulation: PBS with 2% sucrose and 0.09% sodium azide
• Gene Accession No.: Q99578
• Gene Symbols: RIT2
• Immunogen: synthetic peptide directed towards the N terminal region of human RIT2.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG