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Invitrogen™ RIT2 Polyclonal Antibody
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Catalog No. PIPA571336
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100 μL
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PIPA571336 100 μL
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Catalog No. PIPA571336 Supplier Invitrogen™ Supplier No. PA571336
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Description

Rabbit Polyclonal Antibody

RIT2 Polyclonal Antibody for Western Blot

Ras-like without CAAX 2 (RIT2) is a gene located on chromosome 18q12.1, encoding a member of the Ras superfamily of small GTPases. RIT2 is primarily expressed in neuronal tissues, where it plays a crucial role in intracellular signaling pathways that regulate neuronal differentiation, survival, and plasticity. Functionally, RIT2 is involved in neurotrophic factor signaling, contributing to the maintenance and function of the nervous system. This protein interacts with various downstream effectors to influence cellular processes such as growth factor response and neuronal signaling dynamics. Alterations or mutations in RIT2 have been associated with neurological disorders, including Parkinson's disease, implicating its role in neurodegenerative processes. Research into RIT2 aims to elucidate its precise mechanisms in neural signaling and its potential as a therapeutic target for treating neurodegenerative diseases.
TRUSTED_SUSTAINABILITY

Specifications

Antigen RIT2
Applications Western Blot
Classification Polyclonal
Concentration 0.5 mg/mL
Conjugate Unconjugated
Formulation PBS with 2% sucrose and 0.09% sodium azide
Gene RIT2
Gene Accession No. Q99578
Gene Alias GTP-binding protein Rit2; GTP-binding protein Roc2; Ras like without CAAX 2; RAS-like protein expressed in neuron; ras-like protein expressed in neurons; Ras-like without CAAX 1; Ras-like without CAAX 2; ras-like without CAAX protein 2; RIBA; Ric-like, expressed in neurons; RIN; Rit1; RIT2; ROC2
Gene Symbols RIT2
Host Species Rabbit
Immunogen synthetic peptide directed towards the N terminal region of human RIT2.
Purification Method Affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 6014
Target Species Human
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Liquid
Isotype IgG
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