Promotional price valid on web orders only. Your contract pricing may differ. Interested in signing up for a dedicated account number?
Learn More
  1. Home
  2. Products
  3. Antibodies
  4. Primary Antibodies
  5. All Primary Antibodies
  6. PIPA584888

Invitrogen™ RIT2 Polyclonal Antibody
GREENER_CHOICE

Catalog No. PIPA584888
Change view
Click to view available options
Quantity:
100 μL
1 product options available for selection
Product selection table with 1 available options. Use arrow keys to navigate and Enter or Space to select.
Catalog No. Quantity
PIPA584888 100 μL
Use arrow keys to navigate between rows. Press Enter or Space to select a product option. 1 options available.
1 options
Catalog No. PIPA584888 Supplier Invitrogen™ Supplier No. PA584888
Add to Cart
Add to Cart

Description

Rabbit Polyclonal Antibody

Immunogen sequence: MEVENEASCS PGSASGGSRE YKVVM Highest antigen sequence indentity to the following orthologs: Rat - 84%, Mouse - 88%.

Ras-like without CAAX 2 (RIT2) is a gene located on chromosome 18q12.1, encoding a member of the Ras superfamily of small GTPases. RIT2 is primarily expressed in neuronal tissues, where it plays a crucial role in intracellular signaling pathways that regulate neuronal differentiation, survival, and plasticity. Functionally, RIT2 is involved in neurotrophic factor signaling, contributing to the maintenance and function of the nervous system. This protein interacts with various downstream effectors to influence cellular processes such as growth factor response and neuronal signaling dynamics. Alterations or mutations in RIT2 have been associated with neurological disorders, including Parkinson's disease, implicating its role in neurodegenerative processes. Research into RIT2 aims to elucidate its precise mechanisms in neural signaling and its potential as a therapeutic target for treating neurodegenerative diseases.
TRUSTED_SUSTAINABILITY

Specifications

Antigen RIT2
Applications Immunohistochemistry (Paraffin)
Classification Polyclonal
Concentration 0.1 mg/mL
Conjugate Unconjugated
Formulation PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
Gene RIT2
Gene Accession No. Q99578
Gene Alias GTP-binding protein Rit2; GTP-binding protein Roc2; Ras like without CAAX 2; RAS-like protein expressed in neuron; ras-like protein expressed in neurons; Ras-like without CAAX 1; Ras-like without CAAX 2; ras-like without CAAX protein 2; RIBA; Ric-like, expressed in neurons; RIN; Rit1; RIT2; ROC2
Gene Symbols RIT2
Host Species Rabbit
Immunogen Recombinant protein corresponding to Human RIT2. Recombinant protein control fragment (Product #RP-108595).
Purification Method Antigen affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 6014
Target Species Human
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
Show More Show Less

Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov
Product Title
Select an issue

By clicking Submit, you acknowledge that you may be contacted by Fisher Scientific in regards to the feedback you have provided in this form. We will not share your information for any other purposes. All contact information provided shall also be maintained in accordance with our Privacy Policy.