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RITA, Tocris Bioscience™ Available on GSA/VA Contract for Federal Government customers only.

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Quantity:
10mg
1mg
This item is not returnable. View return policy
213261-59-7
C14H12O3S2
292.367
KZENBFUSKMWCJF-UHFFFAOYSA-N
rita,rita nsc 652287,p53 activator iii, rita,5,5'-2,5-furandiyl bis-2-thiophenemethanol,sos bismethanol,rita nsc652287,rita nsc 652287,5,5'-furan-2,5-diyl bis thiophene-5,2-diyl dimethanol,2,5-bis-5-hydroxymethyl-2-thienyl-furan,reactivation of p53 and induction of tumor cell apoptosis
374536
[5-[5-[5-(hydroxymethyl)thiophen-2-yl]furan-2-yl]thiophen-2-yl]methanol
C1=C(SC(=C1)C2=CC=C(O2)C3=CC=C(S3)CO)CO
This item is not returnable. View return policy
213261-59-7
C14H12O3S2
292.367
KZENBFUSKMWCJF-UHFFFAOYSA-N
rita,rita nsc 652287,p53 activator iii, rita,5,5'-2,5-furandiyl bis-2-thiophenemethanol,sos bismethanol,rita nsc652287,rita nsc 652287,5,5'-furan-2,5-diyl bis thiophene-5,2-diyl dimethanol,2,5-bis-5-hydroxymethyl-2-thienyl-furan,reactivation of p53 and induction of tumor cell apoptosis
374536
[5-[5-[5-(hydroxymethyl)thiophen-2-yl]furan-2-yl]thiophen-2-yl]methanol
C1=C(SC(=C1)C2=CC=C(O2)C3=CC=C(S3)CO)CO

MDM2-p53 interaction inhibitor

Anti-tumor agent that binds wild-type p53 (K d = 1.5 nM) preventing p53-MDM2 (HDM2) interaction. Induces p53 accumulation and stimulates apoptosis in tumor cell lines expressing wild-type p53 in vitro and in vivo. Inhibits HPV-E6-mediated proteasomal degradation. Suppresses expression of cervical carcinoma HeLa xenografts in vivo.

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Quantity 1mg
Formula Weight 292.37
Percent Purity >97%
Chemical Name or Material RITA

Recommended Storage : Store at -20°C